Benzo(a)pyrene Enhanced Dermatophagoides Group 1 (Der f 1)-Induced TGFβ1 Signaling Activation Through the Aryl Hydrocarbon Receptor–RhoA Axis in Asthma

We have previously demonstrated that benzo(a)pyrene (BaP) co-exposure with dermatophagoides group 1 allergen (Der f 1) can potentiate Der f 1-induced airway inflammation. The underlying mechanism, however, remains undetermined. Here we investigated the molecular mechanisms underlying the potentiatio...

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Detalles Bibliográficos
Autores principales: Wang, Eryi, Tu, Wei, Do, Danh C., Xiao, Xiaojun, Bhatti, Shehar B., Yang, Liteng, Sun, Xizhuo, Xu, Damo, Yang, Pingchang, Huang, Shau-Ku, Gao, Peisong, Liu, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081905/
https://www.ncbi.nlm.nih.gov/pubmed/33936062
http://dx.doi.org/10.3389/fimmu.2021.643260

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