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CRISPR/Cas9介导的microRNA-21敲除对慢性髓性白血病细胞伊马替尼敏感性的影响
OBJECTIVE: To observe the effects of miR-21 knockout on proliferation and drug resistance in K562/G01 cells, and to preliminarily explore the mechanism of imatinib sensitivity by knocking out miR-21 in K562/G01 cells. METHODS: Using CRISPR/Cas9 to knock out the miR-21 gene in K562/G01 cells, and sin...
| Formato: | Online Artículo Texto |
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| Lenguaje: | English |
| Publicado: |
Editorial office of Chinese Journal of Hematology
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081948/ https://www.ncbi.nlm.nih.gov/pubmed/33910311 http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2021.03.011 |