CRISPAltRations: a validated cloud-based approach for interrogation of double-strand break repair mediated by CRISPR genome editing

CRISPR systems enable targeted genome editing in a wide variety of organisms by introducing single- or double-strand DNA breaks, which are repaired using endogenous molecular pathways. Characterization of on- and off-target editing events from CRISPR proteins can be evaluated using targeted genome r...

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Detalles Bibliográficos
Autores principales: Kurgan, Gavin, Turk, Rolf, Li, Heng, Roberts, Nathan, Rettig, Garrett R., Jacobi, Ashley M., Tso, Lauren, Sturgeon, Morgan, Mertens, Massimo, Noten, Roel, Florus, Kurt, Behlke, Mark A., Wang, Yu, McNeill, Matthew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082044/
https://www.ncbi.nlm.nih.gov/pubmed/33981780
http://dx.doi.org/10.1016/j.omtm.2021.03.024

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