Cargando…

Lung-protective ventilation increases cerebral metabolism and non-inflammatory brain injury in porcine experimental sepsis

BACKGROUND: Protective ventilation with lower tidal volumes reduces systemic and organ-specific inflammation. In sepsis-induced encephalopathy or acute brain injury the use of protective ventilation has not been widely investigated (experimentally or clinically). We hypothesized that protective vent...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nyberg, Axel, Gremo, Erik, Blixt, Jonas, Sperber, Jesper, Larsson, Anders, Lipcsey, Miklós, Pikwer, Andreas, Castegren, Markus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082058/ https://www.ncbi.nlm.nih.gov/pubmed/33926378 http://dx.doi.org/10.1186/s12868-021-00629-0

Ejemplares similares

Lung Protective Ventilation Induces Immunotolerance and Nitric Oxide Metabolites in Porcine Experimental Postoperative Sepsis
por: Sperber, Jesper, et al.
Publicado: (2013)

Evaluating the effects of protective ventilation on organ-specific cytokine production in porcine experimental postoperative sepsis
por: Sperber, Jesper, et al.
Publicado: (2015)

Lung-protective ventilation suppresses systemic and hepatic vein levels of cell-free DNA in porcine experimental post-operative sepsis
por: Nyberg, Axel, et al.
Publicado: (2020)

Pre-exposure to mechanical ventilation and endotoxemia increases Pseudomonas aeruginosa growth in lung tissue during experimental porcine pneumonia
por: Sperber, Jesper, et al.
Publicado: (2020)

Protective ventilation reduces Pseudomonas aeruginosa growth in lung tissue in a porcine pneumonia model
por: Sperber, Jesper, et al.
Publicado: (2017)

Lung-protective ventilation suppresses plasma levels of cell-free DNA in porcine experimental postoperative sepsis
por: Nyberg, A, et al.
Publicado: (2014)

Protective ventilation reduces bacterial growth and lung injury in a porcine pneumonia model
por: Sperber, J, et al.
Publicado: (2014)

Effect of protective ventilation on organ-specific cytokine production in an experimental postoperative sepsis model
por: Sperber, J, et al.
Publicado: (2013)

Pre-exposure to mechanical ventilation and endotoxin influence bacterial growth and immune response during experimental ventilator-associated pneumonia
por: Sperber, J, et al.
Publicado: (2015)

Differential pulmonary and circulatory effects of preventive lung protective ventilation in an experimental postoperative sepsis model
por: Sperber, J, et al.
Publicado: (2012)

An experimental porcine model of invasive candidiasis
por: Krifors, Anders, et al.
Publicado: (2023)

Beneficial Antimicrobial Effect of the Addition of an Aminoglycoside to a β-Lactam Antibiotic in an E. coli Porcine Intensive Care Severe Sepsis Model
por: Skorup, Paul, et al.
Publicado: (2014)

Endotoxin Tolerance Variation over 24 h during Porcine Endotoxemia: Association with Changes in Circulation and Organ Dysfunction
por: Castegren, Markus, et al.
Publicado: (2013)

The impact of the systemic inflammatory response on hepatic bacterial elimination in experimental abdominal sepsis
por: Hanslin, Katja, et al.
Publicado: (2019)

Effect of mechanical ventilation versus spontaneous breathing on abdominal edema and inflammation in ARDS: an experimental porcine model
por: Marchesi, Silvia, et al.
Publicado: (2020)

Pre-existing systemic inflammation attenuates bacterial clearance by the liver in porcine abdominal sepsis
por: Hanslin, K, et al.
Publicado: (2015)

The Patient's Gender Influencing the Accuracy of Diagnosis and Proposed Sepsis Treatment in Constructed Cases
por: Pikwer, Andreas, et al.
Publicado: (2020)

Enhanced bacterial clearance in early secondary sepsis in a porcine intensive care model
por: Wilske, Frida, et al.
Publicado: (2023)

Mode of bacterial killing affects the inflammatory response and associated organ dysfunctions in a porcine E. coli intensive care sepsis model
por: Skorup, Paul, et al.
Publicado: (2020)

The Contribution of Plasma Urea to Total Osmolality During Iatrogenic Fluid Reduction in Critically Ill Patients
por: Nihlén, Sandra, et al.
Publicado: (2021)

TNFR1, TNFR2, neutrophil gelatinase-associated lipocalin and heparin binding protein in identifying sepsis and predicting outcome in an intensive care cohort
por: Bergquist, Maria, et al.
Publicado: (2020)

Endotoxin neutralization and anti-inflammatory effects of tobramycin and ceftazidime in porcine endotoxin shock
por: Goscinski, Gunilla, et al.
Publicado: (2004)

The effect of hemorrhagic shock and intraosseous adrenaline injection on the delivery of a subsequently administered drug - an experimental study
por: Eriksson, Mats, et al.
Publicado: (2019)

Duodenum edema due to reduced lymphatic drainage leads to increased inflammation in a porcine endotoxemic model
por: Marchesi, Silvia, et al.
Publicado: (2022)

Anti-inflammatory effects of the antibiotics ceftazidime and tobramycin in porcine endotoxin shock: are they really anti-inflammatory? Authors' response
por: Goscinski, Gunilla, et al.
Publicado: (2004)

Is cystatin C reliable in the anesthetized pig? An experimental study with special reference to septic shock
por: Eriksson, M, et al.
Publicado: (2012)

Analysis of thromboelastography, PT, APTT and fibrinogen in intraosseous and venous samples—an experimental study
por: Strandberg, Gunnar, et al.
Publicado: (2016)

Effects of surgery and propofol-remifentanil total intravenous anesthesia on cerebrospinal fluid biomarkers of inflammation, Alzheimer’s disease, and neuronal injury in humans: a cohort study
por: Pikwer, Andreas, et al.
Publicado: (2017)

Urine Hydrogen Peroxide Levels and Their Relation to Outcome in Patients with Sepsis, Septic Shock, and Major Burn Injury
por: Lipcsey, Miklos, et al.
Publicado: (2022)

A Comparison between Endostatin and Conventional Biomarkers on 30-Day Mortality and Renal Replacement Therapy in Unselected Intensive Care Patients
por: Ruge, Toralph, et al.
Publicado: (2021)

A non-linear mixed effect model for innate immune response: In vivo kinetics of endotoxin and its induction of the cytokines tumor necrosis factor alpha and interleukin-6
por: Thorsted, Anders, et al.
Publicado: (2019)

Severely deranged vital signs as triggers for acute treatment modifications on an intensive care unit in a low-income country
por: Schell, Carl Otto, et al.
Publicado: (2015)

Erratum to: Severely deranged vital signs as triggers for acute treatment modifications on an intensive care unit in a low-income country
por: Schell, Carl Otto, et al.
Publicado: (2017)

Significant differences when using creatinine, modification of diet in renal disease, or cystatin C for estimating glomerular filtration rate in ICU patients
por: Lipcsey, Miklós, et al.
Publicado: (2011)

Rapid testing of red blood cell parameters in primary care patients using HemoScreen™ point of care instrument
por: Larsson, Anders, et al.
Publicado: (2019)

Effects of extensive bleeding in pigs on laboratory biomarkers
por: Larsson, Anders, et al.
Publicado: (2021)

Intravenous anti-P. aeruginosa IgY-antibodies do not decrease pulmonary bacterial concentrations in a porcine model of ventilator-associated pneumonia
por: Otterbeck, A., et al.
Publicado: (2022)

A comparison of impact of comorbidities and demographics on 60-day mortality in ICU patients with COVID-19, sepsis and acute respiratory distress syndrome
por: Ahlström, Björn, et al.
Publicado: (2022)

Effects of tigecycline and doxycycline in porcine endotoxemia
por: Von Seth, M, et al.
Publicado: (2011)

Vital Signs Directed Therapy: Improving Care in an Intensive Care Unit in a Low-Income Country
por: Baker, Tim, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_pcm4bj0n9f1spurk4nn9aci4bc