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TLR7 and IL-6 differentially regulate the effects of rotarod exercise on the transcriptomic profile and neurogenesis to influence anxiety and memory

Voluntary exercise is well known to benefit brain performance. In contrast, forced exercise induces inflammation-related stress responses and may cause psychiatric disorders. Here, we unexpectedly found that rotarod testing, a frequently applied assay for evaluating rodent motor coordination, induce...

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Detalles Bibliográficos
Autores principales: Hung, Yun-Fen, Hsueh, Yi-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082089/
https://www.ncbi.nlm.nih.gov/pubmed/33981972
http://dx.doi.org/10.1016/j.isci.2021.102384