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Circulating Bile Acids in Liver Failure Activate TGR5 and Induce Monocyte Dysfunction

BACKGROUND & AIMS: Retention of bile acids in the blood is a hallmark of liver failure. Recent studies have shown that increased serum bile acid levels correlate with bacterial infection and increased mortality. However, the mechanisms by which circulating bile acids influence patient outcomes s...

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Detalles Bibliográficos
Autores principales:	Leonhardt, Julia, Haider, Raphael S., Sponholz, Christoph, Leonhardt, Silke, Drube, Julia, Spengler, Katrin, Mihaylov, Diana, Neugebauer, Sophie, Kiehntopf, Michael, Lambert, Nevin A., Kortgen, Andreas, Bruns, Tony, Tacke, Frank, Hoffmann, Carsten, Bauer, Michael, Heller, Regine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082115/ https://www.ncbi.nlm.nih.gov/pubmed/33545429 http://dx.doi.org/10.1016/j.jcmgh.2021.01.011

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