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CXCR4 and CXCR7 Signaling Pathways: A Focus on the Cross-Talk Between Cancer Cells and Tumor Microenvironment

The chemokine receptor 4 (CXCR4) and 7 (CXCR7) are G-protein-coupled receptors (GPCRs) activated through their shared ligand CXCL12 in multiple human cancers. They play a key role in the tumor/tumor microenvironment (TME) promoting tumor progression, targeting cell proliferation and migration, while...

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Detalles Bibliográficos
Autores principales:	Santagata, Sara, Ieranò, Caterina, Trotta, Anna Maria, Capiluongo, Anna, Auletta, Federica, Guardascione, Giuseppe, Scala, Stefania
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082172/ https://www.ncbi.nlm.nih.gov/pubmed/33937018 http://dx.doi.org/10.3389/fonc.2021.591386

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