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Transvesical Versus Posterior Approach to Retzius-Sparing Robot-Assisted Radical Prostatectomy: A Retrospective Comparison With a 12-Month Follow-Up
OBJECTIVES: To assess the perioperative, functional, and oncological outcomes of transvesical robot-assisted radical prostatectomy (T-RARP) and posterior robot-assisted radical prostatectomy (P-RARP) for localized prostate cancer. MATERIALS AND METHODS: We analyzed the data of 96 patients who underw...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082308/ https://www.ncbi.nlm.nih.gov/pubmed/33937043 http://dx.doi.org/10.3389/fonc.2021.641887 |
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author | Deng, Wen Zhang, Cheng Jiang, Hao Li, Yulei Zhu, Ke Liu, Xiaoqiang Chen, Luyao Liu, Weipeng Guo, Ju Zhou, Xiaochen Fu, Bin Wang, Gongxian |
author_facet | Deng, Wen Zhang, Cheng Jiang, Hao Li, Yulei Zhu, Ke Liu, Xiaoqiang Chen, Luyao Liu, Weipeng Guo, Ju Zhou, Xiaochen Fu, Bin Wang, Gongxian |
author_sort | Deng, Wen |
collection | PubMed |
description | OBJECTIVES: To assess the perioperative, functional, and oncological outcomes of transvesical robot-assisted radical prostatectomy (T-RARP) and posterior robot-assisted radical prostatectomy (P-RARP) for localized prostate cancer. MATERIALS AND METHODS: We analyzed the data of 96 patients who underwent T-RARP or P-RARP for localized prostate cancer between January 2017 and June 2019 in a retrospective fashion. RESULTS: No significant differences in the baseline characteristics existed between the T-RARP and P-RARP arms. Both interventions were successfully performed without open conversion in either group. T-RARP was associated with a slightly more operative time (135.3 vs. 127.3 min) and estimated blood loss (105.2 vs. 94.2 mL) than P-RARP, but the differences were not significant (both p > 0.05). The likelihood of transfusion, ≤Grade II, and >Grade II postoperative complications, pT3a disease and positive surgical margins in the T-RARP group was comparable with that in the P-RARP group. No significant differences were noted between these two arms in terms of UC at the removal of catheter and nocturia (p = 0.750 and p = 0.684, respectively), and all included patients recovered UC at 3 months postoperatively. The median International Index of Erectile Function-5 score in both groups remains comparable before and after RARP. The patients in the T-RARP and P-RARP groups had a similar biochemical recurrence-free survival (p = 0.387). CONCLUSIONS: Both T-RARP and P-RARP by experienced hands are feasible for well-selected patients with prostate cancer, obtaining similar outcomes in terms of perioperative results, UC and erectile function, and oncological control within short-term follow-up. |
format | Online Article Text |
id | pubmed-8082308 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-80823082021-04-30 Transvesical Versus Posterior Approach to Retzius-Sparing Robot-Assisted Radical Prostatectomy: A Retrospective Comparison With a 12-Month Follow-Up Deng, Wen Zhang, Cheng Jiang, Hao Li, Yulei Zhu, Ke Liu, Xiaoqiang Chen, Luyao Liu, Weipeng Guo, Ju Zhou, Xiaochen Fu, Bin Wang, Gongxian Front Oncol Oncology OBJECTIVES: To assess the perioperative, functional, and oncological outcomes of transvesical robot-assisted radical prostatectomy (T-RARP) and posterior robot-assisted radical prostatectomy (P-RARP) for localized prostate cancer. MATERIALS AND METHODS: We analyzed the data of 96 patients who underwent T-RARP or P-RARP for localized prostate cancer between January 2017 and June 2019 in a retrospective fashion. RESULTS: No significant differences in the baseline characteristics existed between the T-RARP and P-RARP arms. Both interventions were successfully performed without open conversion in either group. T-RARP was associated with a slightly more operative time (135.3 vs. 127.3 min) and estimated blood loss (105.2 vs. 94.2 mL) than P-RARP, but the differences were not significant (both p > 0.05). The likelihood of transfusion, ≤Grade II, and >Grade II postoperative complications, pT3a disease and positive surgical margins in the T-RARP group was comparable with that in the P-RARP group. No significant differences were noted between these two arms in terms of UC at the removal of catheter and nocturia (p = 0.750 and p = 0.684, respectively), and all included patients recovered UC at 3 months postoperatively. The median International Index of Erectile Function-5 score in both groups remains comparable before and after RARP. The patients in the T-RARP and P-RARP groups had a similar biochemical recurrence-free survival (p = 0.387). CONCLUSIONS: Both T-RARP and P-RARP by experienced hands are feasible for well-selected patients with prostate cancer, obtaining similar outcomes in terms of perioperative results, UC and erectile function, and oncological control within short-term follow-up. Frontiers Media S.A. 2021-04-15 /pmc/articles/PMC8082308/ /pubmed/33937043 http://dx.doi.org/10.3389/fonc.2021.641887 Text en Copyright © 2021 Deng, Zhang, Jiang, Li, Zhu, Liu, Chen, Liu, Guo, Zhou, Fu and Wang https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Oncology Deng, Wen Zhang, Cheng Jiang, Hao Li, Yulei Zhu, Ke Liu, Xiaoqiang Chen, Luyao Liu, Weipeng Guo, Ju Zhou, Xiaochen Fu, Bin Wang, Gongxian Transvesical Versus Posterior Approach to Retzius-Sparing Robot-Assisted Radical Prostatectomy: A Retrospective Comparison With a 12-Month Follow-Up |
title | Transvesical Versus Posterior Approach to Retzius-Sparing Robot-Assisted Radical Prostatectomy: A Retrospective Comparison With a 12-Month Follow-Up |
title_full | Transvesical Versus Posterior Approach to Retzius-Sparing Robot-Assisted Radical Prostatectomy: A Retrospective Comparison With a 12-Month Follow-Up |
title_fullStr | Transvesical Versus Posterior Approach to Retzius-Sparing Robot-Assisted Radical Prostatectomy: A Retrospective Comparison With a 12-Month Follow-Up |
title_full_unstemmed | Transvesical Versus Posterior Approach to Retzius-Sparing Robot-Assisted Radical Prostatectomy: A Retrospective Comparison With a 12-Month Follow-Up |
title_short | Transvesical Versus Posterior Approach to Retzius-Sparing Robot-Assisted Radical Prostatectomy: A Retrospective Comparison With a 12-Month Follow-Up |
title_sort | transvesical versus posterior approach to retzius-sparing robot-assisted radical prostatectomy: a retrospective comparison with a 12-month follow-up |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082308/ https://www.ncbi.nlm.nih.gov/pubmed/33937043 http://dx.doi.org/10.3389/fonc.2021.641887 |
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