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Tension promotes kinetochore–microtubule release by Aurora B kinase
To ensure accurate chromosome segregation, interactions between kinetochores and microtubules are regulated by a combination of mechanics and biochemistry. Tension provides a signal to discriminate attachment errors from bi-oriented kinetochores with sisters correctly attached to opposite spindle po...
Autores principales: | Chen, Geng-Yuan, Renda, Fioranna, Zhang, Huaiying, Gokden, Alper, Wu, Daniel Z., Chenoweth, David M., Khodjakov, Alexey, Lampson, Michael A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082439/ https://www.ncbi.nlm.nih.gov/pubmed/33904910 http://dx.doi.org/10.1083/jcb.202007030 |
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