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Curcumin-primed human BMSC-derived extracellular vesicles reverse IL-1β-induced catabolic responses of OA chondrocytes by upregulating miR-126-3p
BACKGROUND: Curcumin has anti-inflammatory effects and qualifies as a potential candidate for the treatment of osteoarthritis (OA). However, curcumin has limited bioavailability. Extracellular vesicles (EVs) are released by multiple cell types and act as molecule carrier during intercellular communi...
Autores principales: | Li, Shushan, Stöckl, Sabine, Lukas, Christoph, Herrmann, Marietta, Brochhausen, Christoph, König, Matthias A., Johnstone, Brian, Grässel, Susanne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082633/ https://www.ncbi.nlm.nih.gov/pubmed/33926561 http://dx.doi.org/10.1186/s13287-021-02317-6 |
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