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Curcumin-primed human BMSC-derived extracellular vesicles reverse IL-1β-induced catabolic responses of OA chondrocytes by upregulating miR-126-3p

BACKGROUND: Curcumin has anti-inflammatory effects and qualifies as a potential candidate for the treatment of osteoarthritis (OA). However, curcumin has limited bioavailability. Extracellular vesicles (EVs) are released by multiple cell types and act as molecule carrier during intercellular communi...

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Detalles Bibliográficos
Autores principales: Li, Shushan, Stöckl, Sabine, Lukas, Christoph, Herrmann, Marietta, Brochhausen, Christoph, König, Matthias A., Johnstone, Brian, Grässel, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082633/
https://www.ncbi.nlm.nih.gov/pubmed/33926561
http://dx.doi.org/10.1186/s13287-021-02317-6

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