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N-terminal heterogeneity of parenchymal and vascular amyloid-β deposits in Alzheimer’s disease
AIMS: The deposition of amyloid-β (Aβ) peptides in the form of extracellular plaques in the brain represents one of the classical hallmarks of Alzheimer’s disease (AD). In addition to ‘full-length’ Aβ starting with aspartic acid (Asp-1), considerable amounts of various shorter, N-terminally truncate...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082844/ https://www.ncbi.nlm.nih.gov/pubmed/32497293 http://dx.doi.org/10.1111/nan.12637 |