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The emerging role of β-secretases in cancer

BACE1 and BACE2 belong to a class of proteases called β-secretases involved in ectodomain shedding of different transmembrane substrates. These enzymes have been extensively studied in Alzheimer's disease as they are responsible for the processing of APP in neurotoxic Aβ peptides. These proteas...

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Detalles Bibliográficos
Autores principales:	Farris, Francesco, Matafora, Vittoria, Bachi, Angela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082908/ https://www.ncbi.nlm.nih.gov/pubmed/33926496 http://dx.doi.org/10.1186/s13046-021-01953-3

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