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Recovery of new-onset kidney disease in COVID-19 patients discharged from hospital

BACKGROUND: Coronavirus disease 2019 (COVID-19) has emerged as a major global health threat with a great number of deaths worldwide. Despite abundant data on that many COVID-19 patients also displayed kidney disease, there is limited information available about the recovery of kidney disease after d...

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Autores principales: Zhang, Nan-Hui, Cheng, Yi-Chun, Luo, Ran, Zhang, Chun-Xiu, Ge, Shu-Wang, Xu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8083091/
https://www.ncbi.nlm.nih.gov/pubmed/33926392
http://dx.doi.org/10.1186/s12879-021-06105-8
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author Zhang, Nan-Hui
Cheng, Yi-Chun
Luo, Ran
Zhang, Chun-Xiu
Ge, Shu-Wang
Xu, Gang
author_facet Zhang, Nan-Hui
Cheng, Yi-Chun
Luo, Ran
Zhang, Chun-Xiu
Ge, Shu-Wang
Xu, Gang
author_sort Zhang, Nan-Hui
collection PubMed
description BACKGROUND: Coronavirus disease 2019 (COVID-19) has emerged as a major global health threat with a great number of deaths worldwide. Despite abundant data on that many COVID-19 patients also displayed kidney disease, there is limited information available about the recovery of kidney disease after discharge. METHODS: Retrospective and prospective cohort study to patients with new-onset kidney disease during the COVID-19 hospitalization, admitted between January 28 to February 26, 2020. The median follow-up was 4 months after discharge. The follow-up patients were divided into the recovery group and non-recovery group. Descriptive statistics and between-groups comparison were used. RESULTS: In total, 143 discharged patients with new-onset kidney disease during the COVID-19 hospitalization were included. Patients had a median age was 64 (IQR, 51–70) years, and 59.4% of patients were men. During 4-months median follow-up, 91% (130 of 143) patients recovered from kidney disease, and 9% (13 of 143) patients haven’t recovered. The median age of patients in the non-recovery group was 72 years, which was significantly higher than the median age of 62 years in the recovery group. Discharge serum creatinine was significantly higher in the non-recovery group than in the recovery group. CONCLUSIONS: Most of the new-onset kidney diseases during hospitalization of COVID-19 patients recovered 4 months after discharge. We recommend that COVID-19 patients with new-onset kidney disease be followed after discharge to assess kidney recovery, especially elderly patients or patients with high discharge creatinine. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12879-021-06105-8.
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spelling pubmed-80830912021-04-30 Recovery of new-onset kidney disease in COVID-19 patients discharged from hospital Zhang, Nan-Hui Cheng, Yi-Chun Luo, Ran Zhang, Chun-Xiu Ge, Shu-Wang Xu, Gang BMC Infect Dis Research BACKGROUND: Coronavirus disease 2019 (COVID-19) has emerged as a major global health threat with a great number of deaths worldwide. Despite abundant data on that many COVID-19 patients also displayed kidney disease, there is limited information available about the recovery of kidney disease after discharge. METHODS: Retrospective and prospective cohort study to patients with new-onset kidney disease during the COVID-19 hospitalization, admitted between January 28 to February 26, 2020. The median follow-up was 4 months after discharge. The follow-up patients were divided into the recovery group and non-recovery group. Descriptive statistics and between-groups comparison were used. RESULTS: In total, 143 discharged patients with new-onset kidney disease during the COVID-19 hospitalization were included. Patients had a median age was 64 (IQR, 51–70) years, and 59.4% of patients were men. During 4-months median follow-up, 91% (130 of 143) patients recovered from kidney disease, and 9% (13 of 143) patients haven’t recovered. The median age of patients in the non-recovery group was 72 years, which was significantly higher than the median age of 62 years in the recovery group. Discharge serum creatinine was significantly higher in the non-recovery group than in the recovery group. CONCLUSIONS: Most of the new-onset kidney diseases during hospitalization of COVID-19 patients recovered 4 months after discharge. We recommend that COVID-19 patients with new-onset kidney disease be followed after discharge to assess kidney recovery, especially elderly patients or patients with high discharge creatinine. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12879-021-06105-8. BioMed Central 2021-04-29 /pmc/articles/PMC8083091/ /pubmed/33926392 http://dx.doi.org/10.1186/s12879-021-06105-8 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Zhang, Nan-Hui
Cheng, Yi-Chun
Luo, Ran
Zhang, Chun-Xiu
Ge, Shu-Wang
Xu, Gang
Recovery of new-onset kidney disease in COVID-19 patients discharged from hospital
title Recovery of new-onset kidney disease in COVID-19 patients discharged from hospital
title_full Recovery of new-onset kidney disease in COVID-19 patients discharged from hospital
title_fullStr Recovery of new-onset kidney disease in COVID-19 patients discharged from hospital
title_full_unstemmed Recovery of new-onset kidney disease in COVID-19 patients discharged from hospital
title_short Recovery of new-onset kidney disease in COVID-19 patients discharged from hospital
title_sort recovery of new-onset kidney disease in covid-19 patients discharged from hospital
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8083091/
https://www.ncbi.nlm.nih.gov/pubmed/33926392
http://dx.doi.org/10.1186/s12879-021-06105-8
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