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ACE2, TMPRSS2, and L-SIGN Expression in Placentae From HIV-Positive Pregnancies Exposed to Antiretroviral Therapy—Implications for SARS-CoV-2 Placental Infection

BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binding receptor ACE2 and the spike protein priming protease TMPRSS2 are coexpressed in human placentae. It is unknown whether their expression is altered in the context of HIV infection and antiretroviral therapy (ART). METHOD...

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Detalles Bibliográficos
Autores principales: Kala, Smriti, Meteleva, Ksenia, Serghides, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8083191/
https://www.ncbi.nlm.nih.gov/pubmed/33880537
http://dx.doi.org/10.1093/infdis/jiab166