Immunohistochemical detection of 8-hydroxydeoxyguanosine: A biomarker of oxidative DNA damage in oral submucous fibrosis

BACKGROUND: Oral submucous fibrosis (OSMF) is one of the common potentially malignant disorders prevailing in India. The primary etiological factors include tobacco and arecanut, which contain numerous reactive oxygen species (ROS). ROS attack guanine bases in DNA and form 8-hydroxydeoxyguanosine (8...

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Detalles Bibliográficos
Autores principales: Kulasekaran, Chandramohan, Devi, M, Dhivya, K, Vijayalakshmi, D, Sathishkumar, M, Madhanmohan, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8083425/
https://www.ncbi.nlm.nih.gov/pubmed/33967493
http://dx.doi.org/10.4103/jomfp.JOMFP_42_20

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