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Innovative diagnostic approach and investigation trends in COVID19-A systematic review

A highly contagious viral infection emerged in Wuhan city; China had increased mortality with uncertain pathogenesis spreads throughout the world to become a pandemic. It is reported to be caused by a member of β coronaviruses and named it as COVID-19 by the World Health Organization (WHO). The dise...

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Autores principales: Rachel, J Beryl, Gururaj, N, Smitha, T, Daniel, T Divyna, Harishini, B S, Rosaian, Adlin Saroja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8083432/
https://www.ncbi.nlm.nih.gov/pubmed/33967476
http://dx.doi.org/10.4103/jomfp.jomfp_395_20
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author Rachel, J Beryl
Gururaj, N
Smitha, T
Daniel, T Divyna
Harishini, B S
Rosaian, Adlin Saroja
author_facet Rachel, J Beryl
Gururaj, N
Smitha, T
Daniel, T Divyna
Harishini, B S
Rosaian, Adlin Saroja
author_sort Rachel, J Beryl
collection PubMed
description A highly contagious viral infection emerged in Wuhan city; China had increased mortality with uncertain pathogenesis spreads throughout the world to become a pandemic. It is reported to be caused by a member of β coronaviruses and named it as COVID-19 by the World Health Organization (WHO). The disease is caused by a mutant strain of coronavirus SARS-COV-2 that affects the respiratory tract causing mild to severe respiratory tract illness. The clinical manifestation ranges from mild, moderate, severe and very severe signs and symptoms result in death due to severe hypoxia or multi-organ dysfunction. Also, the affected persons were capable of infecting others through various modes of transmission through respiratory droplets (aerosol spread). A definite investigation protocol has followed to diagnose COVID 19 disease but mainly confirmed with reverse transcription polymerase chain reaction. Computerized tomography scan plays a significant role in the diagnosis and prognosis of affected individuals. The major problem with COVID-19 is due to its novelty and lack of vaccination or treatment. This review focuses on the mutation, pathogenesis, various diagnostic tests adopted and autopsy findings in patients affected with COVID-19.
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spelling pubmed-80834322021-05-06 Innovative diagnostic approach and investigation trends in COVID19-A systematic review Rachel, J Beryl Gururaj, N Smitha, T Daniel, T Divyna Harishini, B S Rosaian, Adlin Saroja J Oral Maxillofac Pathol Emerging Hot Topics - Review Article A highly contagious viral infection emerged in Wuhan city; China had increased mortality with uncertain pathogenesis spreads throughout the world to become a pandemic. It is reported to be caused by a member of β coronaviruses and named it as COVID-19 by the World Health Organization (WHO). The disease is caused by a mutant strain of coronavirus SARS-COV-2 that affects the respiratory tract causing mild to severe respiratory tract illness. The clinical manifestation ranges from mild, moderate, severe and very severe signs and symptoms result in death due to severe hypoxia or multi-organ dysfunction. Also, the affected persons were capable of infecting others through various modes of transmission through respiratory droplets (aerosol spread). A definite investigation protocol has followed to diagnose COVID 19 disease but mainly confirmed with reverse transcription polymerase chain reaction. Computerized tomography scan plays a significant role in the diagnosis and prognosis of affected individuals. The major problem with COVID-19 is due to its novelty and lack of vaccination or treatment. This review focuses on the mutation, pathogenesis, various diagnostic tests adopted and autopsy findings in patients affected with COVID-19. Wolters Kluwer - Medknow 2020 2021-01-09 /pmc/articles/PMC8083432/ /pubmed/33967476 http://dx.doi.org/10.4103/jomfp.jomfp_395_20 Text en Copyright: © 2021 Journal of Oral and Maxillofacial Pathology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Emerging Hot Topics - Review Article
Rachel, J Beryl
Gururaj, N
Smitha, T
Daniel, T Divyna
Harishini, B S
Rosaian, Adlin Saroja
Innovative diagnostic approach and investigation trends in COVID19-A systematic review
title Innovative diagnostic approach and investigation trends in COVID19-A systematic review
title_full Innovative diagnostic approach and investigation trends in COVID19-A systematic review
title_fullStr Innovative diagnostic approach and investigation trends in COVID19-A systematic review
title_full_unstemmed Innovative diagnostic approach and investigation trends in COVID19-A systematic review
title_short Innovative diagnostic approach and investigation trends in COVID19-A systematic review
title_sort innovative diagnostic approach and investigation trends in covid19-a systematic review
topic Emerging Hot Topics - Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8083432/
https://www.ncbi.nlm.nih.gov/pubmed/33967476
http://dx.doi.org/10.4103/jomfp.jomfp_395_20
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