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Innovative diagnostic approach and investigation trends in COVID19-A systematic review
A highly contagious viral infection emerged in Wuhan city; China had increased mortality with uncertain pathogenesis spreads throughout the world to become a pandemic. It is reported to be caused by a member of β coronaviruses and named it as COVID-19 by the World Health Organization (WHO). The dise...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8083432/ https://www.ncbi.nlm.nih.gov/pubmed/33967476 http://dx.doi.org/10.4103/jomfp.jomfp_395_20 |
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author | Rachel, J Beryl Gururaj, N Smitha, T Daniel, T Divyna Harishini, B S Rosaian, Adlin Saroja |
author_facet | Rachel, J Beryl Gururaj, N Smitha, T Daniel, T Divyna Harishini, B S Rosaian, Adlin Saroja |
author_sort | Rachel, J Beryl |
collection | PubMed |
description | A highly contagious viral infection emerged in Wuhan city; China had increased mortality with uncertain pathogenesis spreads throughout the world to become a pandemic. It is reported to be caused by a member of β coronaviruses and named it as COVID-19 by the World Health Organization (WHO). The disease is caused by a mutant strain of coronavirus SARS-COV-2 that affects the respiratory tract causing mild to severe respiratory tract illness. The clinical manifestation ranges from mild, moderate, severe and very severe signs and symptoms result in death due to severe hypoxia or multi-organ dysfunction. Also, the affected persons were capable of infecting others through various modes of transmission through respiratory droplets (aerosol spread). A definite investigation protocol has followed to diagnose COVID 19 disease but mainly confirmed with reverse transcription polymerase chain reaction. Computerized tomography scan plays a significant role in the diagnosis and prognosis of affected individuals. The major problem with COVID-19 is due to its novelty and lack of vaccination or treatment. This review focuses on the mutation, pathogenesis, various diagnostic tests adopted and autopsy findings in patients affected with COVID-19. |
format | Online Article Text |
id | pubmed-8083432 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-80834322021-05-06 Innovative diagnostic approach and investigation trends in COVID19-A systematic review Rachel, J Beryl Gururaj, N Smitha, T Daniel, T Divyna Harishini, B S Rosaian, Adlin Saroja J Oral Maxillofac Pathol Emerging Hot Topics - Review Article A highly contagious viral infection emerged in Wuhan city; China had increased mortality with uncertain pathogenesis spreads throughout the world to become a pandemic. It is reported to be caused by a member of β coronaviruses and named it as COVID-19 by the World Health Organization (WHO). The disease is caused by a mutant strain of coronavirus SARS-COV-2 that affects the respiratory tract causing mild to severe respiratory tract illness. The clinical manifestation ranges from mild, moderate, severe and very severe signs and symptoms result in death due to severe hypoxia or multi-organ dysfunction. Also, the affected persons were capable of infecting others through various modes of transmission through respiratory droplets (aerosol spread). A definite investigation protocol has followed to diagnose COVID 19 disease but mainly confirmed with reverse transcription polymerase chain reaction. Computerized tomography scan plays a significant role in the diagnosis and prognosis of affected individuals. The major problem with COVID-19 is due to its novelty and lack of vaccination or treatment. This review focuses on the mutation, pathogenesis, various diagnostic tests adopted and autopsy findings in patients affected with COVID-19. Wolters Kluwer - Medknow 2020 2021-01-09 /pmc/articles/PMC8083432/ /pubmed/33967476 http://dx.doi.org/10.4103/jomfp.jomfp_395_20 Text en Copyright: © 2021 Journal of Oral and Maxillofacial Pathology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Emerging Hot Topics - Review Article Rachel, J Beryl Gururaj, N Smitha, T Daniel, T Divyna Harishini, B S Rosaian, Adlin Saroja Innovative diagnostic approach and investigation trends in COVID19-A systematic review |
title | Innovative diagnostic approach and investigation trends in COVID19-A systematic review |
title_full | Innovative diagnostic approach and investigation trends in COVID19-A systematic review |
title_fullStr | Innovative diagnostic approach and investigation trends in COVID19-A systematic review |
title_full_unstemmed | Innovative diagnostic approach and investigation trends in COVID19-A systematic review |
title_short | Innovative diagnostic approach and investigation trends in COVID19-A systematic review |
title_sort | innovative diagnostic approach and investigation trends in covid19-a systematic review |
topic | Emerging Hot Topics - Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8083432/ https://www.ncbi.nlm.nih.gov/pubmed/33967476 http://dx.doi.org/10.4103/jomfp.jomfp_395_20 |
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