How genetic variation was analyzed in phenytoin-induced gingival enlargement using single-nucleotide polymorphism of candidate gene CYP2C9?

BACKGROUND: Phenytoin-induced gingival overgrowth is an adverse drug reaction affecting few individuals, on phenytoin therapy for its antiepileptic effect. Analysis of genetic variation of CYP2C9*2 gene was done to identify the action of metabolic enzyme cytochrome P 450 on this drug. The main backg...

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Detalles Bibliográficos
Autores principales: Balakrishnan, Premalatha, Ramesh, V, Balamurali, P D, Kennedy Babu, S P K, Prasad, Karthiksree V, Gandhimadhi, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8083442/
https://www.ncbi.nlm.nih.gov/pubmed/33967488
http://dx.doi.org/10.4103/jomfp.JOMFP_273_18

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