The Essential Role of Data and Safety Monitoring Boards (DSMBs) in Ensuring the Ethics of Global Vaccine Trials to Address Coronavirus Disease 2019 (COVID-19O)

Coronavirus disease 2019 (COVID-19) vaccines are being developed and implemented with unprecedented speed. Accordingly, trials considered ethical at their inception may quickly become concerning. We provide recommendations for Data and Safety Monitoring Boards (DSMBs) on monitoring the ethical accep...

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Autores principales: Eckstein, Lisa, Rid, Annette, Kamuya, Dorcas, Shah, Seema K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Viewpoints
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8083612/
https://www.ncbi.nlm.nih.gov/pubmed/33758912
http://dx.doi.org/10.1093/cid/ciab239
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author Eckstein, Lisa
Rid, Annette
Kamuya, Dorcas
Shah, Seema K
author_facet Eckstein, Lisa
Rid, Annette
Kamuya, Dorcas
Shah, Seema K
author_sort Eckstein, Lisa
collection PubMed
description Coronavirus disease 2019 (COVID-19) vaccines are being developed and implemented with unprecedented speed. Accordingly, trials considered ethical at their inception may quickly become concerning. We provide recommendations for Data and Safety Monitoring Boards (DSMBs) on monitoring the ethical acceptability of COVID-19 vaccine trials, focusing on placebo-controlled trials in low- and middle-income countries.
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spelling pubmed-80836122021-05-03 The Essential Role of Data and Safety Monitoring Boards (DSMBs) in Ensuring the Ethics of Global Vaccine Trials to Address Coronavirus Disease 2019 (COVID-19O) Eckstein, Lisa Rid, Annette Kamuya, Dorcas Shah, Seema K Clin Infect Dis Viewpoints Coronavirus disease 2019 (COVID-19) vaccines are being developed and implemented with unprecedented speed. Accordingly, trials considered ethical at their inception may quickly become concerning. We provide recommendations for Data and Safety Monitoring Boards (DSMBs) on monitoring the ethical acceptability of COVID-19 vaccine trials, focusing on placebo-controlled trials in low- and middle-income countries. Oxford University Press 2021-03-24 /pmc/articles/PMC8083612/ /pubmed/33758912 http://dx.doi.org/10.1093/cid/ciab239 Text en © The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Viewpoints
Eckstein, Lisa
Rid, Annette
Kamuya, Dorcas
Shah, Seema K
The Essential Role of Data and Safety Monitoring Boards (DSMBs) in Ensuring the Ethics of Global Vaccine Trials to Address Coronavirus Disease 2019 (COVID-19O)
title The Essential Role of Data and Safety Monitoring Boards (DSMBs) in Ensuring the Ethics of Global Vaccine Trials to Address Coronavirus Disease 2019 (COVID-19O)
title_full The Essential Role of Data and Safety Monitoring Boards (DSMBs) in Ensuring the Ethics of Global Vaccine Trials to Address Coronavirus Disease 2019 (COVID-19O)
title_fullStr The Essential Role of Data and Safety Monitoring Boards (DSMBs) in Ensuring the Ethics of Global Vaccine Trials to Address Coronavirus Disease 2019 (COVID-19O)
title_full_unstemmed The Essential Role of Data and Safety Monitoring Boards (DSMBs) in Ensuring the Ethics of Global Vaccine Trials to Address Coronavirus Disease 2019 (COVID-19O)
title_short The Essential Role of Data and Safety Monitoring Boards (DSMBs) in Ensuring the Ethics of Global Vaccine Trials to Address Coronavirus Disease 2019 (COVID-19O)
title_sort essential role of data and safety monitoring boards (dsmbs) in ensuring the ethics of global vaccine trials to address coronavirus disease 2019 (covid-19o)
topic Viewpoints
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8083612/
https://www.ncbi.nlm.nih.gov/pubmed/33758912
http://dx.doi.org/10.1093/cid/ciab239
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