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FGF21 attenuates hypoxia-induced dysfunction and inflammation in HPAECs via the microRNA-27b-mediated PPARγ pathway
Pulmonary arterial hypertension (PAH), is a chronic and progressive disorder characterized by pulmonary vascular remodeling, including endothelial cell dysfunction and inflammation. MicroRNAs (miRNAs or miRs) play an important role in the development of PAH. In addition, fibroblast growth factor 21...
Autores principales: | Yao, Dan, He, Qinlian, Sun, Junwei, Cai, Luqiong, Wei, Jinqiu, Cai, Gexiang, Liu, Jingjing, Lin, Yinuo, Wang, Liangxing, Huang, Xiaoying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8083827/ https://www.ncbi.nlm.nih.gov/pubmed/33907846 http://dx.doi.org/10.3892/ijmm.2021.4949 |
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