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Hyperglycemia-Induced Dysregulated Fusion Intermediates in Insulin-Secreting Cells Visualized by Super-Resolution Microscopy

Impaired insulin release is a hallmark of type 2 diabetes and is closely related to chronically elevated glucose concentrations, known as “glucotoxicity.” However, the molecular mechanisms by which glucotoxicity impairs insulin secretion remain poorly understood. In addition to known kiss-and-run an...

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Detalles Bibliográficos
Autores principales:	Yang, Guoyi, Li, Liuju, Liu, Yanmei, Liang, Kuo, Wei, Lisi, Chen, Liangyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8083903/ https://www.ncbi.nlm.nih.gov/pubmed/33937248 http://dx.doi.org/10.3389/fcell.2021.650167

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