Tracheomediastinal Fistula Formation After Endobronchial Ultrasound Transbronchial Needle Aspiration While on Bevacizumab Treatment

A 63-year-old male with non-small-cell lung cancer (NSCLC) developed a tracheomediastinal fistula after endobronchial ultrasound transbronchial needle aspiration while on treatment with bevacizumab. This vascular endothelial growth factor-specific angiogenesis inhibitor is a first-line treatment for...

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Detalles Bibliográficos
Autores principales: Castro-Varela, Alejandra, Molina, Sofia, Grosu, Horiana B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8083991/
https://www.ncbi.nlm.nih.gov/pubmed/33936899
http://dx.doi.org/10.7759/cureus.14189
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author Castro-Varela, Alejandra
Molina, Sofia
Grosu, Horiana B
author_facet Castro-Varela, Alejandra
Molina, Sofia
Grosu, Horiana B
author_sort Castro-Varela, Alejandra
collection PubMed
description A 63-year-old male with non-small-cell lung cancer (NSCLC) developed a tracheomediastinal fistula after endobronchial ultrasound transbronchial needle aspiration while on treatment with bevacizumab. This vascular endothelial growth factor-specific angiogenesis inhibitor is a first-line treatment for unresectable or metastatic NSCLC and has been reported to cause fatal non-gastrointestinal fistulas. Respiratory tract fistulas are a known rare complication after bevacizumab therapy characterized by a high mortality rate.
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spelling pubmed-80839912021-04-30 Tracheomediastinal Fistula Formation After Endobronchial Ultrasound Transbronchial Needle Aspiration While on Bevacizumab Treatment Castro-Varela, Alejandra Molina, Sofia Grosu, Horiana B Cureus Internal Medicine A 63-year-old male with non-small-cell lung cancer (NSCLC) developed a tracheomediastinal fistula after endobronchial ultrasound transbronchial needle aspiration while on treatment with bevacizumab. This vascular endothelial growth factor-specific angiogenesis inhibitor is a first-line treatment for unresectable or metastatic NSCLC and has been reported to cause fatal non-gastrointestinal fistulas. Respiratory tract fistulas are a known rare complication after bevacizumab therapy characterized by a high mortality rate. Cureus 2021-03-30 /pmc/articles/PMC8083991/ /pubmed/33936899 http://dx.doi.org/10.7759/cureus.14189 Text en Copyright © 2021, Castro-Varela et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Castro-Varela, Alejandra
Molina, Sofia
Grosu, Horiana B
Tracheomediastinal Fistula Formation After Endobronchial Ultrasound Transbronchial Needle Aspiration While on Bevacizumab Treatment
title Tracheomediastinal Fistula Formation After Endobronchial Ultrasound Transbronchial Needle Aspiration While on Bevacizumab Treatment
title_full Tracheomediastinal Fistula Formation After Endobronchial Ultrasound Transbronchial Needle Aspiration While on Bevacizumab Treatment
title_fullStr Tracheomediastinal Fistula Formation After Endobronchial Ultrasound Transbronchial Needle Aspiration While on Bevacizumab Treatment
title_full_unstemmed Tracheomediastinal Fistula Formation After Endobronchial Ultrasound Transbronchial Needle Aspiration While on Bevacizumab Treatment
title_short Tracheomediastinal Fistula Formation After Endobronchial Ultrasound Transbronchial Needle Aspiration While on Bevacizumab Treatment
title_sort tracheomediastinal fistula formation after endobronchial ultrasound transbronchial needle aspiration while on bevacizumab treatment
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8083991/
https://www.ncbi.nlm.nih.gov/pubmed/33936899
http://dx.doi.org/10.7759/cureus.14189
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AT grosuhorianab tracheomediastinalfistulaformationafterendobronchialultrasoundtransbronchialneedleaspirationwhileonbevacizumabtreatment

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