Castration causes an increase in lysosomal size and upregulation of cathepsin D expression in principal cells along with increased secretion of procathepsin D and prosaposin oligomers in adult rat epididymis

In the epididymis, lysosomal proteins of the epithelial cells are normally targeted from the Golgi apparatus to lysosomes for degradation, although their secretion into the epididymal lumen has been documented and associated with sperm maturation. In this study, cathepsin D (CatD) and prosaposin (PS...

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Detalles Bibliográficos
Autores principales: Carvelli, Lorena, Aguilera, Andrea Carolina, Zyla, Leila, Pereyra, Laura Lucía, Morales, Carlos R., Hermo, Louis, Sosa, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084160/
https://www.ncbi.nlm.nih.gov/pubmed/33914781
http://dx.doi.org/10.1371/journal.pone.0250454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084160/
https://www.ncbi.nlm.nih.gov/pubmed/33914781
http://dx.doi.org/10.1371/journal.pone.0250454

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