Loss-of-function of Fbxo10, encoding a post-translational regulator of BCL2 in lymphomas, has no discernible effect on BCL2 or B lymphocyte accumulation in mice

Regulation of the anti-apoptotic BCL2 protein determines cell survival and is frequently abnormal in B cell lymphomas. An evolutionarily conserved post-translational mechanism for over-expression of BCL2 in human B cell lymphomas and the BCL2 paralogue CED-9 in Caenorhabditis elegans results from lo...

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Detalles Bibliográficos
Autores principales: Masle-Farquhar, Etienne, Russell, Amanda, Li, Yangguang, Zhu, Fen, Rui, Lixin, Brink, Robert, Goodnow, Christopher C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084200/
https://www.ncbi.nlm.nih.gov/pubmed/33914737
http://dx.doi.org/10.1371/journal.pone.0237830

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084200/
https://www.ncbi.nlm.nih.gov/pubmed/33914737
http://dx.doi.org/10.1371/journal.pone.0237830

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