Clinicopathological features of 70 desmoid-type fibromatoses confirmed by β-catenin immunohistochemical staining and CTNNB1 mutation analysis

Desmoid-type fibromatosis (DF) is a locally aggressive neoplasm characterized by mutations in the CTNNB1 gene, which encodes the β-catenin protein. We reviewed 85 cases of DF and performed Sanger sequencing for detecting mutations in CTNNB1 and immunostaining for detecting β-catenin localization. We...

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Detalles Bibliográficos
Autores principales: An, Jiyeon, Woo, Ha Young, Lee, Younghan, Kim, Hyo Song, Jeong, Juhyeon, Kim, Sang Kyum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084228/
https://www.ncbi.nlm.nih.gov/pubmed/33914771
http://dx.doi.org/10.1371/journal.pone.0250619

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