Lipoxin A4 Restores Septic Renal Function via Blocking Crosstalk Between Inflammation and Premature Senescence

Acute kidney injury (AKI) occurs in half of patients with septic shock, resulting in unacceptably high mortality. However, effective preventive treatments are still lacking. We hypothesized that pretreatment with lipoxin A4 (LXA4), known to promote inflammation resolution, may attenuate septic AKI v...

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Detalles Bibliográficos
Autores principales: Chen, Chaojin, Qiu, Rongzong, Yang, Jing, Zhang, Qian, Sun, Guoliang, Gao, Xiaofeng, Hei, Ziqing, Ji, Haocong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084287/
https://www.ncbi.nlm.nih.gov/pubmed/33936050
http://dx.doi.org/10.3389/fimmu.2021.637753

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084287/
https://www.ncbi.nlm.nih.gov/pubmed/33936050
http://dx.doi.org/10.3389/fimmu.2021.637753

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