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Lipoxin A4 Restores Septic Renal Function via Blocking Crosstalk Between Inflammation and Premature Senescence
Acute kidney injury (AKI) occurs in half of patients with septic shock, resulting in unacceptably high mortality. However, effective preventive treatments are still lacking. We hypothesized that pretreatment with lipoxin A4 (LXA4), known to promote inflammation resolution, may attenuate septic AKI v...
Autores principales: | Chen, Chaojin, Qiu, Rongzong, Yang, Jing, Zhang, Qian, Sun, Guoliang, Gao, Xiaofeng, Hei, Ziqing, Ji, Haocong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084287/ https://www.ncbi.nlm.nih.gov/pubmed/33936050 http://dx.doi.org/10.3389/fimmu.2021.637753 |
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