Cargando…
Mechanisms of HIV-1 evasion to the antiviral activity of chemokine CXCL12 indicate potential links with pathogenesis
HIV-1 infects CD4 T lymphocytes (CD4TL) through binding the chemokine receptors CCR5 or CXCR4. CXCR4-using viruses are considered more pathogenic, linked to accelerated depletion of CD4TL and progression to AIDS. However, counterexamples to this paradigm are common, suggesting heterogeneity in the v...
Autores principales: | Armani-Tourret, Marie, Zhou, Zhicheng, Gasser, Romain, Staropoli, Isabelle, Cantaloube-Ferrieu, Vincent, Benureau, Yann, Garcia-Perez, Javier, Pérez-Olmeda, Mayte, Lorin, Valérie, Puissant-Lubrano, Bénédicte, Assoumou, Lambert, Delaugerre, Constance, Lelièvre, Jean-Daniel, Lévy, Yves, Mouquet, Hugo, Martin-Blondel, Guillaume, Alcami, Jose, Arenzana-Seisdedos, Fernando, Izopet, Jacques, Colin, Philippe, Lagane, Bernard |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084328/ https://www.ncbi.nlm.nih.gov/pubmed/33872329 http://dx.doi.org/10.1371/journal.ppat.1009526 |
Ejemplares similares
-
CCR5 structural plasticity shapes HIV-1 phenotypic properties
por: Colin, Philippe, et al.
Publicado: (2018) -
Allosteric regulation by non peptidic, low molecular weight compounds of CCR5 coupling to g-proteins and interaction with Gp120 - consequences on inhibition of R5 HIV-1 infection
por: Rueda, Patricia, et al.
Publicado: (2010) -
HIV-1 cell-to-cell spread overcomes the virus entry block of non-macrophage-tropic strains in macrophages
por: Han, Mingyu, et al.
Publicado: (2022) -
A single-residue change in the HIV-1 V3 loop associated with maraviroc resistance impairs CCR5 binding affinity while increasing replicative capacity
por: Garcia-Perez, Javier, et al.
Publicado: (2015) -
Molecular mechanisms involved in HIV latency and implications for HIV treatment and eradication
por: Alcami, Jose, et al.
Publicado: (2010)