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Sequence deeper without sequencing more: Bayesian resolution of ambiguously mapped reads
Next-generation sequencing (NGS) has transformed molecular biology and contributed to many seminal insights into genomic regulation and function. Apart from whole-genome sequencing, an NGS workflow involves alignment of the sequencing reads to the genome of study, after which the resulting alignment...
Autores principales: | Shah, Rohan N., Ruthenburg, Alexander J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084338/ https://www.ncbi.nlm.nih.gov/pubmed/33872311 http://dx.doi.org/10.1371/journal.pcbi.1008926 |
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