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The landscape of metabolic pathway dependencies in cancer cell lines
The metabolic reprogramming of cancer cells creates metabolic vulnerabilities that can be therapeutically targeted. However, our understanding of metabolic dependencies and the pathway crosstalk that creates these vulnerabilities in cancer cells remains incomplete. Here, by integrating gene expressi...
Autores principales: | Joly, James H., Chew, Brandon T. L., Graham, Nicholas A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084347/ https://www.ncbi.nlm.nih.gov/pubmed/33872312 http://dx.doi.org/10.1371/journal.pcbi.1008942 |
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