Whole-Genome Sequencing of Shiga Toxin–Producing Escherichia coli OX18 from a Fatal Hemolytic Uremic Syndrome Case

We report a fatal case of hemolytic uremic syndrome with urinary tract infection in Japan caused by Shiga toxin–producing Escherichia coli. We genotypically identified the isolate as OX18:H2. Whole-genome sequencing revealed 3 potentially pathogenic lineages (OX18:H2, H19, and H34) that have been co...

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Detalles Bibliográficos
Autores principales: Lee, Kenichi, Iguchi, Atsushi, Uda, Kazuhiro, Matsumura, Sohshi, Miyairi, Isao, Ishikura, Kenji, Ohnishi, Makoto, Seto, Junji, Ishikawa, Kanako, Konishi, Noriko, Obata, Hiromi, Furukawa, Ichiro, Nagaoka, Hiromi, Morinushi, Hirotaka, Hama, Natsuki, Nomoto, Ryohei, Nakajima, Hiroshi, Kariya, Hideaki, Hamasaki, Mitsuhiro, Iyoda, Sunao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2021
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084502/
https://www.ncbi.nlm.nih.gov/pubmed/33900194
http://dx.doi.org/10.3201/eid2705.204162
Descripción
Sumario:We report a fatal case of hemolytic uremic syndrome with urinary tract infection in Japan caused by Shiga toxin–producing Escherichia coli. We genotypically identified the isolate as OX18:H2. Whole-genome sequencing revealed 3 potentially pathogenic lineages (OX18:H2, H19, and H34) that have been continuously isolated in Japan.

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