Longevity of Middle East Respiratory Syndrome Coronavirus Antibody Responses in Humans, Saudi Arabia

Understanding the immune response to Middle East respiratory syndrome coronavirus (MERS-CoV) is crucial for disease prevention and vaccine development. We studied the antibody responses in 48 human MERS-CoV infection survivors who had variable disease severity in Saudi Arabia. MERS-CoV–specific neut...

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Detalles Bibliográficos
Autores principales: Alshukairi, Abeer N., Zhao, Jincun, Al-Mozaini, Maha A., Wang, Yanqun, Dada, Ashraf, Baharoon, Salim A., Alfaraj, Sara, Ahmed, Waleed A., Enani, Mushira A., Elzein, Fatehi E., Eltayeb, Nazik, Layqah, Laila, El-Saed, Aiman, Bahaudden, Husam A., Haseeb, Abdul, El-Kafrawy, Sherif A., Hassan, Ahmed M., Siddiq, Najlaa A., Alsharif, Ibtihaj, Qushmaq, Isamel, Azhar, Esam I., Perlman, Stanley, Memish, Ziad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2021
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084512/
https://www.ncbi.nlm.nih.gov/pubmed/33900908
http://dx.doi.org/10.3201/eid2705.204056
Descripción
Sumario:Understanding the immune response to Middle East respiratory syndrome coronavirus (MERS-CoV) is crucial for disease prevention and vaccine development. We studied the antibody responses in 48 human MERS-CoV infection survivors who had variable disease severity in Saudi Arabia. MERS-CoV–specific neutralizing antibodies were detected for 6 years postinfection.

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