Longevity of Middle East Respiratory Syndrome Coronavirus Antibody Responses in Humans, Saudi Arabia

Understanding the immune response to Middle East respiratory syndrome coronavirus (MERS-CoV) is crucial for disease prevention and vaccine development. We studied the antibody responses in 48 human MERS-CoV infection survivors who had variable disease severity in Saudi Arabia. MERS-CoV–specific neut...

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Autores principales: Alshukairi, Abeer N., Zhao, Jincun, Al-Mozaini, Maha A., Wang, Yanqun, Dada, Ashraf, Baharoon, Salim A., Alfaraj, Sara, Ahmed, Waleed A., Enani, Mushira A., Elzein, Fatehi E., Eltayeb, Nazik, Layqah, Laila, El-Saed, Aiman, Bahaudden, Husam A., Haseeb, Abdul, El-Kafrawy, Sherif A., Hassan, Ahmed M., Siddiq, Najlaa A., Alsharif, Ibtihaj, Qushmaq, Isamel, Azhar, Esam I., Perlman, Stanley, Memish, Ziad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2021
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084512/
https://www.ncbi.nlm.nih.gov/pubmed/33900908
http://dx.doi.org/10.3201/eid2705.204056
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author Alshukairi, Abeer N.
Zhao, Jincun
Al-Mozaini, Maha A.
Wang, Yanqun
Dada, Ashraf
Baharoon, Salim A.
Alfaraj, Sara
Ahmed, Waleed A.
Enani, Mushira A.
Elzein, Fatehi E.
Eltayeb, Nazik
Layqah, Laila
El-Saed, Aiman
Bahaudden, Husam A.
Haseeb, Abdul
El-Kafrawy, Sherif A.
Hassan, Ahmed M.
Siddiq, Najlaa A.
Alsharif, Ibtihaj
Qushmaq, Isamel
Azhar, Esam I.
Perlman, Stanley
Memish, Ziad A.
author_facet Alshukairi, Abeer N.
Zhao, Jincun
Al-Mozaini, Maha A.
Wang, Yanqun
Dada, Ashraf
Baharoon, Salim A.
Alfaraj, Sara
Ahmed, Waleed A.
Enani, Mushira A.
Elzein, Fatehi E.
Eltayeb, Nazik
Layqah, Laila
El-Saed, Aiman
Bahaudden, Husam A.
Haseeb, Abdul
El-Kafrawy, Sherif A.
Hassan, Ahmed M.
Siddiq, Najlaa A.
Alsharif, Ibtihaj
Qushmaq, Isamel
Azhar, Esam I.
Perlman, Stanley
Memish, Ziad A.
author_sort Alshukairi, Abeer N.
collection PubMed
description Understanding the immune response to Middle East respiratory syndrome coronavirus (MERS-CoV) is crucial for disease prevention and vaccine development. We studied the antibody responses in 48 human MERS-CoV infection survivors who had variable disease severity in Saudi Arabia. MERS-CoV–specific neutralizing antibodies were detected for 6 years postinfection.
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spelling pubmed-80845122021-05-11 Longevity of Middle East Respiratory Syndrome Coronavirus Antibody Responses in Humans, Saudi Arabia Alshukairi, Abeer N. Zhao, Jincun Al-Mozaini, Maha A. Wang, Yanqun Dada, Ashraf Baharoon, Salim A. Alfaraj, Sara Ahmed, Waleed A. Enani, Mushira A. Elzein, Fatehi E. Eltayeb, Nazik Layqah, Laila El-Saed, Aiman Bahaudden, Husam A. Haseeb, Abdul El-Kafrawy, Sherif A. Hassan, Ahmed M. Siddiq, Najlaa A. Alsharif, Ibtihaj Qushmaq, Isamel Azhar, Esam I. Perlman, Stanley Memish, Ziad A. Emerg Infect Dis Dispatch Understanding the immune response to Middle East respiratory syndrome coronavirus (MERS-CoV) is crucial for disease prevention and vaccine development. We studied the antibody responses in 48 human MERS-CoV infection survivors who had variable disease severity in Saudi Arabia. MERS-CoV–specific neutralizing antibodies were detected for 6 years postinfection. Centers for Disease Control and Prevention 2021-05 /pmc/articles/PMC8084512/ /pubmed/33900908 http://dx.doi.org/10.3201/eid2705.204056 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Alshukairi, Abeer N.
Zhao, Jincun
Al-Mozaini, Maha A.
Wang, Yanqun
Dada, Ashraf
Baharoon, Salim A.
Alfaraj, Sara
Ahmed, Waleed A.
Enani, Mushira A.
Elzein, Fatehi E.
Eltayeb, Nazik
Layqah, Laila
El-Saed, Aiman
Bahaudden, Husam A.
Haseeb, Abdul
El-Kafrawy, Sherif A.
Hassan, Ahmed M.
Siddiq, Najlaa A.
Alsharif, Ibtihaj
Qushmaq, Isamel
Azhar, Esam I.
Perlman, Stanley
Memish, Ziad A.
Longevity of Middle East Respiratory Syndrome Coronavirus Antibody Responses in Humans, Saudi Arabia
title Longevity of Middle East Respiratory Syndrome Coronavirus Antibody Responses in Humans, Saudi Arabia
title_full Longevity of Middle East Respiratory Syndrome Coronavirus Antibody Responses in Humans, Saudi Arabia
title_fullStr Longevity of Middle East Respiratory Syndrome Coronavirus Antibody Responses in Humans, Saudi Arabia
title_full_unstemmed Longevity of Middle East Respiratory Syndrome Coronavirus Antibody Responses in Humans, Saudi Arabia
title_short Longevity of Middle East Respiratory Syndrome Coronavirus Antibody Responses in Humans, Saudi Arabia
title_sort longevity of middle east respiratory syndrome coronavirus antibody responses in humans, saudi arabia
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084512/
https://www.ncbi.nlm.nih.gov/pubmed/33900908
http://dx.doi.org/10.3201/eid2705.204056
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