Genomic Evidence of SARS-CoV-2 Reinfection Involving E484K Spike Mutation, Brazil

Uncertainty remains about how long the protective immune responses against severe acute respiratory syndrome coronavirus 2 persists, and suspected reinfection in recovered patients has been reported. We describe a case of reinfection from distinct virus lineages in Brazil harboring the E484K mutatio...

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Autores principales: Nonaka, Carolina K. V., Franco, Marília Miranda, Gräf, Tiago, de Lorenzo Barcia, Camila Araújo, de Ávila Mendonça, Renata Naves, de Sousa, Karoline Almeida Felix, Neiva, Leila M. C., Fosenca, Vagner, Mendes, Ana V. A., de Aguiar, Renato Santana, Giovanetti, Marta, de Freitas Souza, Bruno Solano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2021
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084516/
https://www.ncbi.nlm.nih.gov/pubmed/33605869
http://dx.doi.org/10.3201/eid2705.210191
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author Nonaka, Carolina K. V.
Franco, Marília Miranda
Gräf, Tiago
de Lorenzo Barcia, Camila Araújo
de Ávila Mendonça, Renata Naves
de Sousa, Karoline Almeida Felix
Neiva, Leila M. C.
Fosenca, Vagner
Mendes, Ana V. A.
de Aguiar, Renato Santana
Giovanetti, Marta
de Freitas Souza, Bruno Solano
author_facet Nonaka, Carolina K. V.
Franco, Marília Miranda
Gräf, Tiago
de Lorenzo Barcia, Camila Araújo
de Ávila Mendonça, Renata Naves
de Sousa, Karoline Almeida Felix
Neiva, Leila M. C.
Fosenca, Vagner
Mendes, Ana V. A.
de Aguiar, Renato Santana
Giovanetti, Marta
de Freitas Souza, Bruno Solano
author_sort Nonaka, Carolina K. V.
collection PubMed
description Uncertainty remains about how long the protective immune responses against severe acute respiratory syndrome coronavirus 2 persists, and suspected reinfection in recovered patients has been reported. We describe a case of reinfection from distinct virus lineages in Brazil harboring the E484K mutation, a variant associated with escape from neutralizing antibodies.
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spelling pubmed-80845162021-05-11 Genomic Evidence of SARS-CoV-2 Reinfection Involving E484K Spike Mutation, Brazil Nonaka, Carolina K. V. Franco, Marília Miranda Gräf, Tiago de Lorenzo Barcia, Camila Araújo de Ávila Mendonça, Renata Naves de Sousa, Karoline Almeida Felix Neiva, Leila M. C. Fosenca, Vagner Mendes, Ana V. A. de Aguiar, Renato Santana Giovanetti, Marta de Freitas Souza, Bruno Solano Emerg Infect Dis Research Letter Uncertainty remains about how long the protective immune responses against severe acute respiratory syndrome coronavirus 2 persists, and suspected reinfection in recovered patients has been reported. We describe a case of reinfection from distinct virus lineages in Brazil harboring the E484K mutation, a variant associated with escape from neutralizing antibodies. Centers for Disease Control and Prevention 2021-05 /pmc/articles/PMC8084516/ /pubmed/33605869 http://dx.doi.org/10.3201/eid2705.210191 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research Letter
Nonaka, Carolina K. V.
Franco, Marília Miranda
Gräf, Tiago
de Lorenzo Barcia, Camila Araújo
de Ávila Mendonça, Renata Naves
de Sousa, Karoline Almeida Felix
Neiva, Leila M. C.
Fosenca, Vagner
Mendes, Ana V. A.
de Aguiar, Renato Santana
Giovanetti, Marta
de Freitas Souza, Bruno Solano
Genomic Evidence of SARS-CoV-2 Reinfection Involving E484K Spike Mutation, Brazil
title Genomic Evidence of SARS-CoV-2 Reinfection Involving E484K Spike Mutation, Brazil
title_full Genomic Evidence of SARS-CoV-2 Reinfection Involving E484K Spike Mutation, Brazil
title_fullStr Genomic Evidence of SARS-CoV-2 Reinfection Involving E484K Spike Mutation, Brazil
title_full_unstemmed Genomic Evidence of SARS-CoV-2 Reinfection Involving E484K Spike Mutation, Brazil
title_short Genomic Evidence of SARS-CoV-2 Reinfection Involving E484K Spike Mutation, Brazil
title_sort genomic evidence of sars-cov-2 reinfection involving e484k spike mutation, brazil
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084516/
https://www.ncbi.nlm.nih.gov/pubmed/33605869
http://dx.doi.org/10.3201/eid2705.210191
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