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Structure of HIV-1 gp41 with its membrane anchors targeted by neutralizing antibodies

The HIV-1 gp120/gp41 trimer undergoes a series of conformational changes in order to catalyze gp41-induced fusion of viral and cellular membranes. Here, we present the crystal structure of gp41 locked in a fusion intermediate state by an MPER-specific neutralizing antibody. The structure illustrates...

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Detalles Bibliográficos
Autores principales:	Caillat, Christophe, Guilligay, Delphine, Torralba, Johana, Friedrich, Nikolas, Nieva, Jose L, Trkola, Alexandra, Chipot, Christophe J, Dehez, François L, Weissenhorn, Winfried
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2021
Materias:	Microbiology and Infectious Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084527/ https://www.ncbi.nlm.nih.gov/pubmed/33871352 http://dx.doi.org/10.7554/eLife.65005

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