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The Regulating Effect of Autophagy-Related MiRNAs in Kidney, Bladder, and Prostate Cancer
Autophagy is a treatment target for many disorders, including cancer, and its specific role is becoming increasingly well known. In tumors, researchers pay attention to microribonucleic acids (miRNAs) with regulatory effects to develop more effective therapeutic drugs for autophagy and find new ther...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084683/ https://www.ncbi.nlm.nih.gov/pubmed/33976697 http://dx.doi.org/10.1155/2021/5510318 |
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author | Huang, Kai Sun, Xiaoxin Wu, Haotian Zhao, Jun Jian, Yuli Xu, Zhongyang Wang, Shujing Yang, Deyong |
author_facet | Huang, Kai Sun, Xiaoxin Wu, Haotian Zhao, Jun Jian, Yuli Xu, Zhongyang Wang, Shujing Yang, Deyong |
author_sort | Huang, Kai |
collection | PubMed |
description | Autophagy is a treatment target for many disorders, including cancer, and its specific role is becoming increasingly well known. In tumors, researchers pay attention to microribonucleic acids (miRNAs) with regulatory effects to develop more effective therapeutic drugs for autophagy and find new therapeutic targets. Various studies have shown that autophagy-related miRNAs play an irreplaceable role in different tumors, such as miR-495, miR-30, and miR-101. These miRNAs are associated with autophagy resistance in gastric cancer, non-small cell lung cancer, and cervical cancer. In recent years, autophagy-related miRNAs have also been reported to play a role in autophagy in urinary system tumors. This article reviews the regulatory effects of autophagy-related miRNAs in kidney, bladder, and prostate cancer and provides new ideas for targeted therapy of the three major tumors of the urinary system. |
format | Online Article Text |
id | pubmed-8084683 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-80846832021-05-10 The Regulating Effect of Autophagy-Related MiRNAs in Kidney, Bladder, and Prostate Cancer Huang, Kai Sun, Xiaoxin Wu, Haotian Zhao, Jun Jian, Yuli Xu, Zhongyang Wang, Shujing Yang, Deyong J Oncol Review Article Autophagy is a treatment target for many disorders, including cancer, and its specific role is becoming increasingly well known. In tumors, researchers pay attention to microribonucleic acids (miRNAs) with regulatory effects to develop more effective therapeutic drugs for autophagy and find new therapeutic targets. Various studies have shown that autophagy-related miRNAs play an irreplaceable role in different tumors, such as miR-495, miR-30, and miR-101. These miRNAs are associated with autophagy resistance in gastric cancer, non-small cell lung cancer, and cervical cancer. In recent years, autophagy-related miRNAs have also been reported to play a role in autophagy in urinary system tumors. This article reviews the regulatory effects of autophagy-related miRNAs in kidney, bladder, and prostate cancer and provides new ideas for targeted therapy of the three major tumors of the urinary system. Hindawi 2021-04-22 /pmc/articles/PMC8084683/ /pubmed/33976697 http://dx.doi.org/10.1155/2021/5510318 Text en Copyright © 2021 Kai Huang et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Huang, Kai Sun, Xiaoxin Wu, Haotian Zhao, Jun Jian, Yuli Xu, Zhongyang Wang, Shujing Yang, Deyong The Regulating Effect of Autophagy-Related MiRNAs in Kidney, Bladder, and Prostate Cancer |
title | The Regulating Effect of Autophagy-Related MiRNAs in Kidney, Bladder, and Prostate Cancer |
title_full | The Regulating Effect of Autophagy-Related MiRNAs in Kidney, Bladder, and Prostate Cancer |
title_fullStr | The Regulating Effect of Autophagy-Related MiRNAs in Kidney, Bladder, and Prostate Cancer |
title_full_unstemmed | The Regulating Effect of Autophagy-Related MiRNAs in Kidney, Bladder, and Prostate Cancer |
title_short | The Regulating Effect of Autophagy-Related MiRNAs in Kidney, Bladder, and Prostate Cancer |
title_sort | regulating effect of autophagy-related mirnas in kidney, bladder, and prostate cancer |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084683/ https://www.ncbi.nlm.nih.gov/pubmed/33976697 http://dx.doi.org/10.1155/2021/5510318 |
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