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The Regulating Effect of Autophagy-Related MiRNAs in Kidney, Bladder, and Prostate Cancer

Autophagy is a treatment target for many disorders, including cancer, and its specific role is becoming increasingly well known. In tumors, researchers pay attention to microribonucleic acids (miRNAs) with regulatory effects to develop more effective therapeutic drugs for autophagy and find new ther...

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Detalles Bibliográficos
Autores principales: Huang, Kai, Sun, Xiaoxin, Wu, Haotian, Zhao, Jun, Jian, Yuli, Xu, Zhongyang, Wang, Shujing, Yang, Deyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084683/
https://www.ncbi.nlm.nih.gov/pubmed/33976697
http://dx.doi.org/10.1155/2021/5510318
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author Huang, Kai
Sun, Xiaoxin
Wu, Haotian
Zhao, Jun
Jian, Yuli
Xu, Zhongyang
Wang, Shujing
Yang, Deyong
author_facet Huang, Kai
Sun, Xiaoxin
Wu, Haotian
Zhao, Jun
Jian, Yuli
Xu, Zhongyang
Wang, Shujing
Yang, Deyong
author_sort Huang, Kai
collection PubMed
description Autophagy is a treatment target for many disorders, including cancer, and its specific role is becoming increasingly well known. In tumors, researchers pay attention to microribonucleic acids (miRNAs) with regulatory effects to develop more effective therapeutic drugs for autophagy and find new therapeutic targets. Various studies have shown that autophagy-related miRNAs play an irreplaceable role in different tumors, such as miR-495, miR-30, and miR-101. These miRNAs are associated with autophagy resistance in gastric cancer, non-small cell lung cancer, and cervical cancer. In recent years, autophagy-related miRNAs have also been reported to play a role in autophagy in urinary system tumors. This article reviews the regulatory effects of autophagy-related miRNAs in kidney, bladder, and prostate cancer and provides new ideas for targeted therapy of the three major tumors of the urinary system.
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spelling pubmed-80846832021-05-10 The Regulating Effect of Autophagy-Related MiRNAs in Kidney, Bladder, and Prostate Cancer Huang, Kai Sun, Xiaoxin Wu, Haotian Zhao, Jun Jian, Yuli Xu, Zhongyang Wang, Shujing Yang, Deyong J Oncol Review Article Autophagy is a treatment target for many disorders, including cancer, and its specific role is becoming increasingly well known. In tumors, researchers pay attention to microribonucleic acids (miRNAs) with regulatory effects to develop more effective therapeutic drugs for autophagy and find new therapeutic targets. Various studies have shown that autophagy-related miRNAs play an irreplaceable role in different tumors, such as miR-495, miR-30, and miR-101. These miRNAs are associated with autophagy resistance in gastric cancer, non-small cell lung cancer, and cervical cancer. In recent years, autophagy-related miRNAs have also been reported to play a role in autophagy in urinary system tumors. This article reviews the regulatory effects of autophagy-related miRNAs in kidney, bladder, and prostate cancer and provides new ideas for targeted therapy of the three major tumors of the urinary system. Hindawi 2021-04-22 /pmc/articles/PMC8084683/ /pubmed/33976697 http://dx.doi.org/10.1155/2021/5510318 Text en Copyright © 2021 Kai Huang et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Huang, Kai
Sun, Xiaoxin
Wu, Haotian
Zhao, Jun
Jian, Yuli
Xu, Zhongyang
Wang, Shujing
Yang, Deyong
The Regulating Effect of Autophagy-Related MiRNAs in Kidney, Bladder, and Prostate Cancer
title The Regulating Effect of Autophagy-Related MiRNAs in Kidney, Bladder, and Prostate Cancer
title_full The Regulating Effect of Autophagy-Related MiRNAs in Kidney, Bladder, and Prostate Cancer
title_fullStr The Regulating Effect of Autophagy-Related MiRNAs in Kidney, Bladder, and Prostate Cancer
title_full_unstemmed The Regulating Effect of Autophagy-Related MiRNAs in Kidney, Bladder, and Prostate Cancer
title_short The Regulating Effect of Autophagy-Related MiRNAs in Kidney, Bladder, and Prostate Cancer
title_sort regulating effect of autophagy-related mirnas in kidney, bladder, and prostate cancer
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084683/
https://www.ncbi.nlm.nih.gov/pubmed/33976697
http://dx.doi.org/10.1155/2021/5510318
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