MRI-based diagnosis and treatment of pediatric brain tumors: is tissue sample always needed?

Traditional management of newly diagnosed pediatric brain tumors (PBTs) consists of cranial imaging, typically magnetic resonance imaging (MRI), and is frequently followed by tissue diagnosis, through either surgical biopsy or tumor resection. Therapy regimes are typically dependent on histological...

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Autores principales: Soleman, Jehuda, Dvir, Rina, Ben-Sira, Liat, Yalon, Michal, Boop, Frederick, Constantini, Shlomi, Roth, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084800/
https://www.ncbi.nlm.nih.gov/pubmed/33821340
http://dx.doi.org/10.1007/s00381-021-05148-1
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author Soleman, Jehuda
Dvir, Rina
Ben-Sira, Liat
Yalon, Michal
Boop, Frederick
Constantini, Shlomi
Roth, Jonathan
author_facet Soleman, Jehuda
Dvir, Rina
Ben-Sira, Liat
Yalon, Michal
Boop, Frederick
Constantini, Shlomi
Roth, Jonathan
author_sort Soleman, Jehuda
collection PubMed
description Traditional management of newly diagnosed pediatric brain tumors (PBTs) consists of cranial imaging, typically magnetic resonance imaging (MRI), and is frequently followed by tissue diagnosis, through either surgical biopsy or tumor resection. Therapy regimes are typically dependent on histological diagnosis. To date, many treatment regimens are based on molecular biology. The scope of this article is to discuss the role of diagnosis and further treatment of PBTs based solely on MRI features, in light of the latest treatment protocols. Typical MRI findings and indications for surgical biopsy of these lesions are described.
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spelling pubmed-80848002021-05-05 MRI-based diagnosis and treatment of pediatric brain tumors: is tissue sample always needed? Soleman, Jehuda Dvir, Rina Ben-Sira, Liat Yalon, Michal Boop, Frederick Constantini, Shlomi Roth, Jonathan Childs Nerv Syst Review Article Traditional management of newly diagnosed pediatric brain tumors (PBTs) consists of cranial imaging, typically magnetic resonance imaging (MRI), and is frequently followed by tissue diagnosis, through either surgical biopsy or tumor resection. Therapy regimes are typically dependent on histological diagnosis. To date, many treatment regimens are based on molecular biology. The scope of this article is to discuss the role of diagnosis and further treatment of PBTs based solely on MRI features, in light of the latest treatment protocols. Typical MRI findings and indications for surgical biopsy of these lesions are described. Springer Berlin Heidelberg 2021-04-05 2021 /pmc/articles/PMC8084800/ /pubmed/33821340 http://dx.doi.org/10.1007/s00381-021-05148-1 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review Article
Soleman, Jehuda
Dvir, Rina
Ben-Sira, Liat
Yalon, Michal
Boop, Frederick
Constantini, Shlomi
Roth, Jonathan
MRI-based diagnosis and treatment of pediatric brain tumors: is tissue sample always needed?
title MRI-based diagnosis and treatment of pediatric brain tumors: is tissue sample always needed?
title_full MRI-based diagnosis and treatment of pediatric brain tumors: is tissue sample always needed?
title_fullStr MRI-based diagnosis and treatment of pediatric brain tumors: is tissue sample always needed?
title_full_unstemmed MRI-based diagnosis and treatment of pediatric brain tumors: is tissue sample always needed?
title_short MRI-based diagnosis and treatment of pediatric brain tumors: is tissue sample always needed?
title_sort mri-based diagnosis and treatment of pediatric brain tumors: is tissue sample always needed?
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084800/
https://www.ncbi.nlm.nih.gov/pubmed/33821340
http://dx.doi.org/10.1007/s00381-021-05148-1
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