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Dataset for longitudinal evaluation of the Abbott ARCHITECT SARS-CoV-2 IgM and IgG assays in a pediatric population divided by age

BACKGROUND: SARS-CoV-2 infection in children does not seem to follow the same pattern as in adults. Limited information is published on the level of antibody production and the duration of antibody response in children with COVID-19. Moreover, it is unknown if all children have a similar immune resp...

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Autores principales: Interiano, Cristina, Muze, Sheicho, Turner, Brian, Gonzalez, Mark, Rogers, Beverly, Jerris, Robert, Weinzierl, Elizabeth, Elkhalifa, Mohamed, Leung-Pineda, Van
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084914/
https://www.ncbi.nlm.nih.gov/pubmed/33969165
http://dx.doi.org/10.1016/j.dib.2021.107110
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author Interiano, Cristina
Muze, Sheicho
Turner, Brian
Gonzalez, Mark
Rogers, Beverly
Jerris, Robert
Weinzierl, Elizabeth
Elkhalifa, Mohamed
Leung-Pineda, Van
author_facet Interiano, Cristina
Muze, Sheicho
Turner, Brian
Gonzalez, Mark
Rogers, Beverly
Jerris, Robert
Weinzierl, Elizabeth
Elkhalifa, Mohamed
Leung-Pineda, Van
author_sort Interiano, Cristina
collection PubMed
description BACKGROUND: SARS-CoV-2 infection in children does not seem to follow the same pattern as in adults. Limited information is published on the level of antibody production and the duration of antibody response in children with COVID-19. Moreover, it is unknown if all children have a similar immune response to the infection, or if there are age dependent differences. In these data, we look at the IgM and IgG levels and duration of two age groups infected by the SARS-CoV-2 virus. METHODS: Residual laboratory specimens from pediatric patients positive for SARS-CoV-2 infection were tested for IgM and IgG against SARS-CoV-2 using an automated Abbott ARCHITECT i1000. We tested 181 specimens from 41 patients with a positive molecular result. Data was grouped either as time after nucleic acid amplification test (NAAT) or time after symptom onset. Patient samples were divided into 2 age groups: 0 to 11 years old and 12 to 19 years old. The assays detect IgM against the spike protein and IgG against the nucleocapsid protein.
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spelling pubmed-80849142021-05-03 Dataset for longitudinal evaluation of the Abbott ARCHITECT SARS-CoV-2 IgM and IgG assays in a pediatric population divided by age Interiano, Cristina Muze, Sheicho Turner, Brian Gonzalez, Mark Rogers, Beverly Jerris, Robert Weinzierl, Elizabeth Elkhalifa, Mohamed Leung-Pineda, Van Data Brief Data Article BACKGROUND: SARS-CoV-2 infection in children does not seem to follow the same pattern as in adults. Limited information is published on the level of antibody production and the duration of antibody response in children with COVID-19. Moreover, it is unknown if all children have a similar immune response to the infection, or if there are age dependent differences. In these data, we look at the IgM and IgG levels and duration of two age groups infected by the SARS-CoV-2 virus. METHODS: Residual laboratory specimens from pediatric patients positive for SARS-CoV-2 infection were tested for IgM and IgG against SARS-CoV-2 using an automated Abbott ARCHITECT i1000. We tested 181 specimens from 41 patients with a positive molecular result. Data was grouped either as time after nucleic acid amplification test (NAAT) or time after symptom onset. Patient samples were divided into 2 age groups: 0 to 11 years old and 12 to 19 years old. The assays detect IgM against the spike protein and IgG against the nucleocapsid protein. Elsevier 2021-04-30 /pmc/articles/PMC8084914/ /pubmed/33969165 http://dx.doi.org/10.1016/j.dib.2021.107110 Text en © 2021 The Authors. Published by Elsevier Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Data Article
Interiano, Cristina
Muze, Sheicho
Turner, Brian
Gonzalez, Mark
Rogers, Beverly
Jerris, Robert
Weinzierl, Elizabeth
Elkhalifa, Mohamed
Leung-Pineda, Van
Dataset for longitudinal evaluation of the Abbott ARCHITECT SARS-CoV-2 IgM and IgG assays in a pediatric population divided by age
title Dataset for longitudinal evaluation of the Abbott ARCHITECT SARS-CoV-2 IgM and IgG assays in a pediatric population divided by age
title_full Dataset for longitudinal evaluation of the Abbott ARCHITECT SARS-CoV-2 IgM and IgG assays in a pediatric population divided by age
title_fullStr Dataset for longitudinal evaluation of the Abbott ARCHITECT SARS-CoV-2 IgM and IgG assays in a pediatric population divided by age
title_full_unstemmed Dataset for longitudinal evaluation of the Abbott ARCHITECT SARS-CoV-2 IgM and IgG assays in a pediatric population divided by age
title_short Dataset for longitudinal evaluation of the Abbott ARCHITECT SARS-CoV-2 IgM and IgG assays in a pediatric population divided by age
title_sort dataset for longitudinal evaluation of the abbott architect sars-cov-2 igm and igg assays in a pediatric population divided by age
topic Data Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084914/
https://www.ncbi.nlm.nih.gov/pubmed/33969165
http://dx.doi.org/10.1016/j.dib.2021.107110
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