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Geometrically defined environments direct cell division rate and subcellular YAP localization in single mouse embryonic stem cells

Mechanotransduction via yes-associated protein (YAP) is a central mechanism for decision-making in mouse embryonic stem cells (mESCs). Nuclear localization of YAP is tightly connected to pluripotency and increases the cell division rate (CDR). How the geometry of the extracellular environment influe...

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Detalles Bibliográficos
Autores principales:	Bertels, Sarah, Jaggy, Mona, Richter, Benjamin, Keppler, Stephan, Weber, Kerstin, Genthner, Elisa, Fischer, Andrea C., Thiel, Michael, Wegener, Martin, Greiner, Alexandra M., Autenrieth, Tatjana J., Bastmeyer, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084931/ https://www.ncbi.nlm.nih.gov/pubmed/33927254 http://dx.doi.org/10.1038/s41598-021-88336-y

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