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Inhibition of glypican-1 expression induces an activated fibroblast phenotype in a human bone marrow-derived stromal cell-line

Cancer-associated fibroblasts (CAFs) are the most abundant stromal cell type in the tumor microenvironment. CAFs orchestrate tumor-stromal interactions, and contribute to cancer cell growth, metastasis, extracellular matrix (ECM) remodeling, angiogenesis, immunomodulation, and chemoresistance. Howev...

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Detalles Bibliográficos
Autores principales:	Kaur, Sukhneeraj P., Verma, Arti, Lee, Hee. K., Barnett, Lillie M., Somanath, Payaningal R., Cummings, Brian S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8084937/ https://www.ncbi.nlm.nih.gov/pubmed/33927256 http://dx.doi.org/10.1038/s41598-021-88519-7

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