Murine astrovirus tropism for goblet cells and enterocytes facilitates an IFN-λ response in vivo and in enteroid cultures

Although they globally cause viral gastroenteritis in children, astroviruses are understudied due to the lack of well-defined animal models. While murine astroviruses (muAstVs) chronically infect immunodeficient mice, a culture system and understanding of their pathogenesis is lacking. Here, we desc...

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Detalles Bibliográficos
Autores principales: Ingle, Harshad, Hassan, Ebrahim, Gawron, Jana, Mihi, Belgacem, Li, Yuhao, Kennedy, Elizabeth A., Kalugotla, Gowri, Makimaa, Heyde, Lee, Sanghyun, Desai, Pritesh, McDonald, Keely G., Diamond, Michael S., Newberry, Rodney D., Good, Misty, Baldridge, Megan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085034/
https://www.ncbi.nlm.nih.gov/pubmed/33674763
http://dx.doi.org/10.1038/s41385-021-00387-6

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