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Orexinergic descending inhibitory pathway mediates linalool odor-induced analgesia in mice
Linalool odor exposure induces an analgesic effect in mice. This effect disappeared in the anosmic model mice, indicating that olfactory input evoked by linalool odor triggered this effect. Furthermore, hypothalamic orexinergic neurons play a pivotal role in this effect. However, the neuronal circui...
Autores principales: | Higa, Yurina, Kashiwadani, Hideki, Sugimura, Mitsutaka, Kuwaki, Tomoyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085205/ https://www.ncbi.nlm.nih.gov/pubmed/33927235 http://dx.doi.org/10.1038/s41598-021-88359-5 |
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