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Thioredoxin Reductase Is a Valid Target for Antimicrobial Therapeutic Development Against Gram-Positive Bacteria

There is a drought of new antibacterial compounds that exploit novel targets. Thioredoxin reductase (TrxR) from the Gram-positive bacterial antioxidant thioredoxin system has emerged from multiple screening efforts as a potential target for auranofin, ebselen, shikonin, and allicin. Auranofin serves...

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Detalles Bibliográficos
Autores principales:	Felix, LewisOscar, Mylonakis, Eleftherios, Fuchs, Beth Burgwyn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085250/ https://www.ncbi.nlm.nih.gov/pubmed/33936021 http://dx.doi.org/10.3389/fmicb.2021.663481

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