Role of mTOR-Regulated Autophagy in Synaptic Plasticity Related Proteins Downregulation and the Reference Memory Deficits Induced by Anesthesia/Surgery in Aged Mice

Postoperative cognitive dysfunction increases mortality and morbidity in perioperative patients and has become a major concern for patients and caregivers. Previous studies demonstrated that synaptic plasticity is closely related to cognitive function, anesthesia and surgery inhibit synaptic functio...

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Detalles Bibliográficos
Autores principales: Gao, Sunan, Zhang, Siyu, Zhou, Hongmei, Tao, Xiaoyan, Ni, Yunjian, Pei, Daqing, Kang, Shuai, Yan, Weiwei, Lu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085306/
https://www.ncbi.nlm.nih.gov/pubmed/33935683
http://dx.doi.org/10.3389/fnagi.2021.628541

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