Cargando…

MBNL1 Suppressed Cancer Metastatic of Skin Squamous Cell Carcinoma Via by TIAL1/MYOD1/Caspase-9/3 Signaling Pathways

OBJECTIVE: The incidence of skin squamous cell carcinoma (SSCC) has recently been increasing, with diverse clinical manifestations.SSCC could metastasize to lymph nodes or other organs, posing a great threat to life. The present study was designed to investigate the function and underlying mechanism...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Jiaorong, Wang, Jiaqi, Qian, Jingyi, Bao, Mengying, Zhang, Xin, Huang, Zheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085367/ https://www.ncbi.nlm.nih.gov/pubmed/33896245 http://dx.doi.org/10.1177/1533033820960755

Ejemplares similares

Autoregulation of MBNL1 function by exon 1 exclusion from MBNL1 transcript
por: Konieczny, Patryk, et al.
Publicado: (2017)

Mbnl1 and Mbnl2 regulate brain structural integrity in mice
por: Sta Maria, Naomi S., et al.
Publicado: (2021)

Phenylbutazone induces expression of MBNL1 and suppresses formation of MBNL1-CUG RNA foci in a mouse model of myotonic dystrophy
por: Chen, Guiying, et al.
Publicado: (2016)

Identification of MBNL1 and MBNL3 domains required for splicing activation and repression
por: Grammatikakis, Ioannis, et al.
Publicado: (2011)

Alternative splicing mediates the compensatory upregulation of MBNL2 upon MBNL1 loss-of-function
por: Nitschke, Larissa, et al.
Publicado: (2023)

RNA Splicing Is Responsive to MBNL1 Dose
por: Jog, Sonali P., et al.
Publicado: (2012)

LncRNA MBNL1-AS1 Represses Proliferation and Cancer Stem-Like Properties of Breast Cancer through MBNL1-AS1/ZFP36/CENPA Axis
por: Ding, Yu, et al.
Publicado: (2022)

Mice lacking MBNL1 and MBNL2 exhibit sudden cardiac death and molecular signatures recapitulating myotonic dystrophy
por: Lee, Kuang-Yung, et al.
Publicado: (2022)

(CTG)n repeat-mediated dysregulation of MBNL1 and MBNL2 expression during myogenesis in DM1 occurs already at the myoblast stage
por: André, Laurène M., et al.
Publicado: (2019)

MBNL1(42) and MBNL1(43) gene isoforms, overexpressed in DM1-patient muscle, encode for nuclear proteins interacting with Src family kinases
por: Botta, A, et al.
Publicado: (2013)

MBNL1 and PTB cooperate to repress splicing of Tpm1 exon 3
por: Gooding, Clare, et al.
Publicado: (2013)

MBNL1 alternative splicing isoforms play opposing roles in cancer
por: Tabaglio, Tommaso, et al.
Publicado: (2018)

Loss of MBNL1 induces RNA misprocessing in the thymus and peripheral blood
por: Sznajder, Łukasz J., et al.
Publicado: (2020)

MBNL1 regulates isoproterenol‐induced myocardial remodelling in vitro and in vivo
por: Xu, Yao, et al.
Publicado: (2020)

Mechanistic determinants of MBNL activity
por: Sznajder, Łukasz J., et al.
Publicado: (2016)

CUGBP1 and MBNL1 preferentially bind to 3′ UTRs and facilitate mRNA decay
por: Masuda, Akio, et al.
Publicado: (2012)

MBNL1 binds GC motifs embedded in pyrimidines to regulate alternative splicing
por: Goers, Emily S., et al.
Publicado: (2010)

Loss of MBNL1-mediated retrograde BDNF signaling in the myotonic dystrophy brain
por: Wang, Pei-Ying, et al.
Publicado: (2023)

Calcitriol increases MBNL1 expression and alleviates myotonic dystrophy phenotypes in HSA(LR) mouse models
por: Huang, Kun, et al.
Publicado: (2022)

MBNL expression in autoregulatory feedback loops
por: Konieczny, Patryk, et al.
Publicado: (2017)

The Presence of Two MyoD Genes in a Subset of Acanthopterygii Fish Is Associated with a Polyserine Insert in MyoD1
por: White, Lewis J., et al.
Publicado: (2023)

HuR and TIA1/TIAL1 Are Involved in Regulation of Alternative Splicing of SIRT1 Pre-mRNA
por: Zhao, Wenhui, et al.
Publicado: (2014)

Myod1 and GR coordinate myofiber-specific transcriptional enhancers
por: Rovito, Daniela, et al.
Publicado: (2021)

Lomofungin and dilomofungin: inhibitors of MBNL1-CUG RNA binding with distinct cellular effects
por: Hoskins, Jason W., et al.
Publicado: (2014)

MBNL1-mediated regulation of differentiation RNAs promotes myofibroblast transformation and the fibrotic response
por: Davis, Jennifer, et al.
Publicado: (2015)

The RNA hairpin binder TRIM71 modulates alternative splicing by repressing MBNL1
por: Welte, Thomas, et al.
Publicado: (2019)

Alternative splicing analysis in human monocytes and macrophages reveals MBNL1 as major regulator
por: Liu, Hongfei, et al.
Publicado: (2018)

MBNL1 regulates essential alternative RNA splicing patterns in MLL-rearranged leukemia
por: Itskovich, Svetlana S., et al.
Publicado: (2020)

MBNL‐dependent impaired development within the neuromuscular system in myotonic dystrophy type 1
por: Tahraoui‐Bories, Julie, et al.
Publicado: (2023)

RBFOX1 Cooperates with MBNL1 to Control Splicing in Muscle, Including Events Altered in Myotonic Dystrophy Type 1
por: Klinck, Roscoe, et al.
Publicado: (2014)

MeCP2 Promotes Gastric Cancer Progression Through Regulating FOXF1/Wnt5a/β-Catenin and MYOD1/Caspase-3 Signaling Pathways
por: Zhao, Lingyu, et al.
Publicado: (2017)

NFIB-Mediated lncRNA PVT1 Aggravates Laryngeal Squamous Cell Carcinoma Progression via the miR-1301-3p/MBNL1 Axis
por: Tang, Tian, et al.
Publicado: (2021)

Up-regulation of long noncoding RNA MBNL1-AS1 suppresses breast cancer progression by modulating miR-423-5p/CREBZF axis
por: Fang, Jun, et al.
Publicado: (2022)

LncRNA MBNL1-AS1 Suppresses Cell Proliferation and Metastasis of Pancreatic Adenocarcinoma through Targeting Carcinogenic miR-301b-3p
por: Sulidankazha, Chouman, et al.
Publicado: (2023)

Fishing for answers: MBNL2 in myotonic dystrophy
Publicado: (2011)

Calcium Homeostasis in Myogenic Differentiation Factor 1 (MyoD)-Transformed, Virally-Transduced, Skin-Derived Equine Myotubes
por: Fernandez-Fuente, Marta, et al.
Publicado: (2014)

MBNL and CELF proteins regulate alternative splicing of the skeletal muscle chloride channel CLCN1
por: Kino, Yoshihiro, et al.
Publicado: (2009)

Single-molecule study of the CUG repeat–MBNL1 interaction and its inhibition by small molecules
por: Haghighat Jahromi, Amin, et al.
Publicado: (2013)

Autistic traits in myotonic dystrophy type 1 due to MBNL inhibition and RNA mis-splicing
por: Sznajder, Lukasz, et al.
Publicado: (2023)

MYOD-1 in normal colonic mucosa – role as a putative biomarker?
por: Arasaradnam, Ramesh P, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_emogops9n2o4c84sirlnep16tv