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miR-376a Provokes Rectum Adenocarcinoma Via CTC1 Depletion-Induced Telomere Dysfunction

CTC1 is a component of the mammalian CST (CTC1–STN1–TEN1) complex which plays essential roles in resolving replication problems to facilitate telomeric DNA and genomic DNA replication. We previously reported that the depletion of CTC1 leads to stalled replication fork restart defects. Moreover, the...

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Detalles Bibliográficos
Autores principales:	Liu, Yang, Zhao, Xiaotong, Wang, Bing, Liu, Zhijia, Zhang, Manman, Wang, Jinhan, Xu, Chang, Wang, Yan, Du, Liqing, Wang, Feng, Wang, Qin, Liu, Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085492/ https://www.ncbi.nlm.nih.gov/pubmed/33937245 http://dx.doi.org/10.3389/fcell.2021.649328

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