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Genomic Risk Factors Driving Immune-Mediated Delayed Drug Hypersensitivity Reactions

Adverse drug reactions (ADRs) remain associated with significant mortality. Delayed hypersensitivity reactions (DHRs) that occur greater than 6 h following drug administration are T-cell mediated with many severe DHRs now associated with human leukocyte antigen (HLA) risk alleles, opening pathways f...

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Detalles Bibliográficos
Autores principales:	Li, Yueran, Deshpande, Pooja, Hertzman, Rebecca J., Palubinsky, Amy M., Gibson, Andrew, Phillips, Elizabeth J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085493/ https://www.ncbi.nlm.nih.gov/pubmed/33936169 http://dx.doi.org/10.3389/fgene.2021.641905

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