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Large-Scale Gene Expression Signatures Reveal a Microbicidal Pattern of Activation in Mycobacterium leprae-Infected Monocyte-Derived Macrophages With Low Multiplicity of Infection
Leprosy is a disease with a clinical spectrum of presentations that is also manifested in diverse histological features. At one pole, lepromatous lesions (L-pole) have phagocytic foamy macrophages heavily parasitized with freely multiplying intracellular Mycobacterium leprae. At the other pole, the...
Autores principales: | Leal-Calvo, Thyago, Martins, Bruna Leticia, Bertoluci, Daniele Ferreira, Rosa, Patricia Sammarco, de Camargo, Rodrigo Mendes, Germano, Giovanna Vale, Brito de Souza, Vania Nieto, Pereira Latini, Ana Carla, Moraes, Milton Ozório |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085500/ https://www.ncbi.nlm.nih.gov/pubmed/33936067 http://dx.doi.org/10.3389/fimmu.2021.647832 |
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