Cargando…

Improved Survival and Retinal Function of Aging ZDF Rats in Long-Term, Uncontrolled Diabetes by BGP-15 Treatment

Retinal complications of diabetes often lead to deterioration or even loss of vision. This hastens discovery of pharmacological agents able to counterbalance diabetic retinopathy. BGP-15, an emerging small molecule agent, was formerly proven by our workgroup to be retinoprotective on nonobese diabet...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wachal, Zita, Szilágyi, Anna, Takács, Barbara, Szabó, Adrienn Mónika, Priksz, Dániel, Bombicz, Mariann, Szilvássy, Judit, Juhász, Béla, Szilvássy, Zoltán, Varga, Balázs
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085539/ https://www.ncbi.nlm.nih.gov/pubmed/33935754 http://dx.doi.org/10.3389/fphar.2021.650207

Ejemplares similares

Corrigendum: Improved survival and retinal function of aging ZDF rats in long-term, uncontrolled diabetes by BGP-15 treatment
por: Wachal, Zita, et al.
Publicado: (2022)

Cardioprotective Role of BGP-15 in Ageing Zucker Diabetic Fatty Rat (ZDF) Model: Extended Mitochondrial Longevity
por: Kozma, Mate, et al.
Publicado: (2022)

Retinoprotection by BGP-15, a Hydroximic Acid Derivative, in a Type II Diabetic Rat Model Compared to Glibenclamide, Metformin, and Pioglitazone
por: Wachal, Zita, et al.
Publicado: (2020)

Negative Inotropic Effect of BGP-15 on the Human Right Atrial Myocardium
por: Lampé, Nóra, et al.
Publicado: (2020)

The Drug Candidate BGP-15 Delays the Onset of Diastolic Dysfunction in the Goto-Kakizaki Rat Model of Diabetic Cardiomyopathy
por: Bombicz, Mariann, et al.
Publicado: (2019)

Drug Candidate BGP-15 Prevents Isoproterenol-Induced Arrhythmias and Alters Heart Rate Variability (HRV) in Telemetry-Implanted Rats
por: Bernat, Brigitta, et al.
Publicado: (2023)

Therapeutic Properties of Ayahuasca Components in Ischemia/Reperfusion Injury of the Eye
por: Szilágyi, Anna, et al.
Publicado: (2022)

Examination of Preferences for COVID-19 Vaccines in Hungary Based on Their Properties—Examining the Impact of Pandemic Awareness with a Hybrid Choice Approach
por: Blaga, Zsanett, et al.
Publicado: (2023)

A Novel Therapeutic Approach in the Treatment of Pulmonary Arterial Hypertension: Allium ursinum Liophylisate Alleviates Symptoms Comparably to Sildenafil
por: Bombicz, Mariann, et al.
Publicado: (2017)

The effect of a long-term treatment with cannabidiol-rich hemp extract oil on the adenosinergic system of the zucker diabetic fatty (ZDF) rat atrium
por: Viczjan, Gabor, et al.
Publicado: (2022)

Upregulation of Myocardial and Vascular Phosphodiesterase 9A in A Model of Atherosclerotic Cardiovascular Disease
por: Priksz, Daniel, et al.
Publicado: (2018)

Therapeutic Aspects of Prunus cerasus Extract in a Rabbit Model of Atherosclerosis-Associated Diastolic Dysfunction
por: Szekeres, Reka, et al.
Publicado: (2023)

Heme Oxygenase-1 Activity as a Correlate to Exercise-Mediated Amelioration of Cognitive Decline and Neuropathological Alterations in an Aging Rat Model of Dementia
por: Kurucz, Andrea, et al.
Publicado: (2018)

BGP-15 Inhibits Hyperglycemia-Aggravated VSMC Calcification Induced by High Phosphate
por: Nagy, Annamária, et al.
Publicado: (2021)

Long Term Osmotic Mini Pump Treatment with Alpha-MSH Improves Myocardial Function in Zucker Diabetic Fatty Rats
por: Szokol, Miklos, et al.
Publicado: (2017)

A Body of Circumstantial Evidence for the Irreversible Ectonucleotidase Inhibitory Action of FSCPX, an Agent Known as a Selective Irreversible A(1) Adenosine Receptor Antagonist So Far
por: Viczjan, Gabor, et al.
Publicado: (2021)

Protective Effect of Prunus Cerasus (Sour Cherry) Seed Extract on the Recovery of Ischemia/Reperfusion-Induced Retinal Damage in Zucker Diabetic Fatty Rat
por: Varga, Balázs, et al.
Publicado: (2017)

Pharmacological Overview of the BGP-15 Chemical Agent as a New Drug Candidate for the Treatment of Symptoms of Metabolic Syndrome
por: Pető, Ágota, et al.
Publicado: (2020)

Fenugreek (Trigonella Foenum-Graecum) Seed Flour and Diosgenin Preserve Endothelium-Dependent Arterial Relaxation in a Rat Model of Early-Stage Metabolic Syndrome
por: Szabó, Katalin, et al.
Publicado: (2018)

Efficacy of Pre- and Post-Treatment by Topical Formulations Containing Dissolved and Suspended Silybum marianum against UVB-Induced Oxidative Stress in Guinea Pig and on HaCaT Keratinocytes
por: Fehér, Pálma, et al.
Publicado: (2016)

Protective Effect of Alpha-Melanocyte-Stimulating Hormone (α-MSH) on the Recovery of Ischemia/Reperfusion (I/R)-Induced Retinal Damage in A Rat Model
por: Varga, Balazs, et al.
Publicado: (2013)

Insulin-Sensitizer Effects of Fenugreek Seeds in Parallel with Changes in Plasma MCH Levels in Healthy Volunteers
por: Kiss, Rita, et al.
Publicado: (2018)

An Advanced in Silico Modelling of the Interaction between FSCPX, an Irreversible A(1) Adenosine Receptor Antagonist, and NBTI, a Nucleoside Transport Inhibitor, in the Guinea Pig Atrium
por: Szabo, Adrienn Monika, et al.
Publicado: (2019)

FSCPX, a Chemical Widely Used as an Irreversible A(1) Adenosine Receptor Antagonist, Modifies the Effect of NBTI, a Nucleoside Transport Inhibitor, by Reducing the Interstitial Adenosine Level in the Guinea Pig Atrium
por: Erdei, Tamas, et al.
Publicado: (2018)

Adverse Impact of Diet-Induced Hypercholesterolemia on Cardiovascular Tissue Homeostasis in a Rabbit Model: Time-Dependent Changes in Cardiac Parameters
por: Kertész, Attila, et al.
Publicado: (2013)

Alpha–Melanocyte-stimulating Hormone Induces Vasodilation and Exerts Cardioprotection Through the Heme-Oxygenase Pathway in Rat Hearts
por: Vecsernyes, Miklos, et al.
Publicado: (2017)

Anti-Atherogenic Properties of Allium ursinum Liophylisate: Impact on Lipoprotein Homeostasis and Cardiac Biomarkers in Hypercholesterolemic Rabbits
por: Bombicz, Mariann, et al.
Publicado: (2016)

Cardioprotective Effect of Selective Estrogen Receptor Modulator Raloxifene Are Mediated by Heme Oxygenase in Estrogen-Deficient Rat
por: Posa, Anikó, et al.
Publicado: (2017)

Accuracy and Precision of the Receptorial Responsiveness Method (RRM) in the Quantification of A(1) Adenosine Receptor Agonists
por: Szabo, Adrienn Monika, et al.
Publicado: (2019)

The Melanin-concentrating Hormone System in Human, Rodent and Avian Brain
por: Bencze, János, et al.
Publicado: (2018)

SIRT1 Activation by Equisetum arvense L. (Horsetail) Modulates Insulin Sensitivity in Streptozotocin Induced Diabetic Rats
por: Hegedűs, Csaba, et al.
Publicado: (2020)

Methodical Challenges and a Possible Resolution in the Assessment of Receptor Reserve for Adenosine, an Agonist with Short Half-Life
por: Zsuga, Judit, et al.
Publicado: (2017)

The Novel Cardiac Myosin Activator Danicamtiv Improves Cardiac Systolic Function at the Expense of Diastolic Dysfunction In Vitro and In Vivo: Implications for Clinical Applications
por: Ráduly, Arnold Péter, et al.
Publicado: (2022)

BGP
por: Van Beijnum, Iljitsch
Publicado: (2002)

Unpredictable In Vitro Killing Activity of Amphotericin B against Four Candida auris Clades
por: Papp, Zoltán, et al.
Publicado: (2021)

Practical BGP
por: White, Russ, et al.
Publicado: (2005)

Troubleshooting BGP: a practical guide to understanding and troubleshooting BGP
por: Jain, Vinit, et al.
Publicado: (2017)

Versatile routing and services with BGP: understanding and implementing BGP in SR-OS
por: Alcatel-Lucent, et al.
Publicado: (2014)

BGP in the data center
por: Dutt, Dinesh G
Publicado: (2017)

BGP design and implementation
por: Zhang, Randy, et al.
Publicado: (2004)

Cannot write session to /tmp/vufind_sessions/sess_qicap21pme6d8brcmapn5a9f51