A Super-Enhancer Driven by FOSL1 Controls miR-21-5p Expression in Head and Neck Squamous Cell Carcinoma

MiR-21-5p is one of the most common oncogenic miRNAs that is upregulated in many solid cancers by inhibiting its target genes at the posttranscriptional level. However, the upstream regulatory mechanisms of miR-21-5p are still not well documented in cancers. Here, we identify a super-enhancer associ...

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Detalles Bibliográficos
Autores principales: Wan, Yuehan, Hoyle, Rosalie G., Xie, Nan, Wang, Wenjin, Cai, Hongshi, Zhang, Ming, Ma, Zhikun, Xiong, Gan, Xu, Xiuyun, Huang, Zhengxian, Liu, Xiqiang, Li, Jiong, Wang, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085558/
https://www.ncbi.nlm.nih.gov/pubmed/33937067
http://dx.doi.org/10.3389/fonc.2021.656628

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