Cargando…
The Role of PDE8 in T Cell Recruitment and Function in Inflammation
Inhibitors targeting cyclic nucleotide phosphodiesterases (PDEs) expressed in leukocytes have entered clinical practice to treat inflammatory disorders, with three PDE4 inhibitors currently in clinical use as therapeutics for psoriasis, psoriatic arthritis, atopic dermatitis and chronic obstructive...
Autores principales: | Epstein, Paul M., Basole, Chaitali, Brocke, Stefan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085600/ https://www.ncbi.nlm.nih.gov/pubmed/33937235 http://dx.doi.org/10.3389/fcell.2021.636778 |
Ejemplares similares
-
Differential Expression and Function of PDE8 and PDE4 in Effector T cells: Implications for PDE8 as a Drug Target in Inflammation
por: Vang, Amanda G., et al.
Publicado: (2016) -
Treatment of Experimental Autoimmune Encephalomyelitis with an Inhibitor of Phosphodiesterase-8 (PDE8)
por: Basole, Chaitali P., et al.
Publicado: (2022) -
Editorial: Imaging and Mechanism of Leukocyte Recruitment and Function in Inflammation and Infections
por: Sun, Hao, et al.
Publicado: (2021) -
Complement Receptors and Their Role in Leukocyte Recruitment and Phagocytosis
por: Vandendriessche, Sofie, et al.
Publicado: (2021) -
Loss of Pde6a Induces Rod Outer Segment Shrinkage and Visual Alterations in pde6a(Q70X) Mutant Zebrafish, a Relevant Model of Retinal Dystrophy
por: Crouzier, Lucie, et al.
Publicado: (2021)